Effect of erythropoietin on the survival of retinal neurocytes in culture upon serum withdrawal

YS Zhong, HP Yao, LF Deng, Y Cheng, YJ Min - Neurosciences Journal, 2010 - nsj.org.sa
OBJECTIVE: To clarify whether erythropoietin (EPO) could substitute for the serum
component in cultured retinal neurocytes suffering from serum withdrawal. METHODS: The …

Expression pattern of erythropoietin and erythropoietin receptor in experimental model of retinal detachment

Z Xie, X Wu, Q Qiu, Y Gong, Y Song, Q Gu… - Current eye …, 2007 - Taylor & Francis
Purpose: Erythropoietin (EPO), known for its role in erythroid cell differentiation, has been
suggested to have a neuroprotective effect on retinal neurons. The aim of the current study …

Erythropoietin Prevents Glutamate–induced Retinal Ganglion Cell Death

M Yamasaki, T Inaba, K Murata… - … & Visual Science, 2004 - iovs.arvojournals.org
Purpose: Erythropoietin (Epo) has been reported to protect not only erythroid progenitors but
also neurons from apoptosis. Because retinal ganglion cell (RGC) death is one of the …

Effect of systemic erythropoietin treatment on photoreceptors degeneration of RCS rats.

K Bigot, E Perez, S Gadin, O Roche… - … & Visual Science, 2004 - iovs.arvojournals.org
Purpose: Erythropoietin (Epo) is recognized for its central role in differentiation and
proliferation of erythroid precursor cells. Nevertheless, recent studies reported that Epo also …

Promotion of neurite outgrowth and protective effect of erythropoietin on the retinal neurons of rats

Y Zhong, H Yao, L Deng, Y Cheng, X Zhou - Graefe's archive for clinical …, 2007 - Springer
Objective To clarify the effect of erythropoietin (EPO) on neurite outgrowth of the cultured
retinal neurocytes, and investigate whether EPO might potentially be beneficial in protecting …

Protection of endogenous erythropoietin on photoreceptor cells in retinal detachment and its mechanism

C Fang, C ZHUANG, W Jian, HUA Xin… - Chinese Journal of …, 2011 - pesquisa.bvsalud.org
Background Erythropoietin (EPO) has a protective effect on retinal neurons in many retinal
diseases, but regarding the effect of EPO on apoptosis of retinal photoreceptor cells in …

Neuroprotective effects of erythropoietin on glutamate and nitric oxide toxicity in primary cultured retinal ganglion cells

M Yamasaki, HK Mishima, H Yamashita, K Kashiwagi… - Brain research, 2005 - Elsevier
Erythropoietin receptor (EpoR) is expressed in the central nervous system (CNS), however,
no clear consensus has been obtained whether Epo acts as a prosurvival factor in neurons …

[HTML][HTML] Effect of erythropoietin axotomy-induced apoptosis in rat retinal ganglion cells

JH Weishaupt, G Rohde, E Pölking… - … & visual science, 2004 - iovs.arvojournals.org
purpose. Erythropoietin (EPO) modulates erythropoiesis by inhibiting apoptosis in
erythrocyte progenitors. Recently, EPO has been shown to be protective in experimental …

Effects of supplemental erythropoietin on its receptor expression and signal transduction pathways in rat model of retinal detachment

Z Xie, F Chen, X Wu, C Zhuang, J Zhu… - Current Eye …, 2012 - Taylor & Francis
Purpose: The aim of this study was to investigate the effects of supplemental erythropoietin
(EPO) on its receptor (EPOR) and signal transduction pathways in rat model of retinal …

[HTML][HTML] Safety and efficacy of intravitreal injection of recombinant erythropoietin for protection of photoreceptor cells in a rat model of retinal detachment

Z Xie, F Chen, X Wu, C Zhuang, J Zhu, J Wang, H Ji… - Eye, 2012 - nature.com
Purpose To elucidate the safety and efficacy of exogenous erythropoietin (EPO) for the
protection of photoreceptor cells in a rat model of retinal detachment (RD). Methods …