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Research ArticleORIGINAL ARTICLES
Open Access

Decreased handgrip strength and increased hip osteoporosis in patients with Alzheimer’s disease

Figen Ayhan, Feray Soyupek, Burak Tonuk, Figen Gokoglu and Rezan Yorgancioglu
Neurosciences Journal April 2007, 12 (2) 140-144;
Figen Ayhan
Department of Physical Medicine and Rehabilitation, Ankara Education and Research Hospital, Ankara, Turkey. Tel. +90 (312) 343 8595. Fax. +90 (312) 363 3396. E-mail: [email protected] / [email protected]
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Feray Soyupek
Department of Physical Medicine and Rehabilitation, Ankara Education and Research Hospital, Ankara, Turkey. Tel. +90 (312) 343 8595. Fax. +90 (312) 363 3396. E-mail: [email protected] / [email protected]
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Burak Tonuk
Department of Physical Medicine and Rehabilitation, Ankara Education and Research Hospital, Ankara, Turkey. Tel. +90 (312) 343 8595. Fax. +90 (312) 363 3396. E-mail: [email protected] / [email protected]
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Figen Gokoglu
Department of Physical Medicine and Rehabilitation, Ankara Education and Research Hospital, Ankara, Turkey. Tel. +90 (312) 343 8595. Fax. +90 (312) 363 3396. E-mail: [email protected] / [email protected]
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Rezan Yorgancioglu
Department of Physical Medicine and Rehabilitation, Ankara Education and Research Hospital, Ankara, Turkey. Tel. +90 (312) 343 8595. Fax. +90 (312) 363 3396. E-mail: [email protected] / [email protected]
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Abstract

OBJECTIVE: To evaluate the causes of disability in the musculoskeletal system, and depression in patients with Alzheimer’s disease (AD) and healthy controls.

METHODS: A case-controlled study in which healthy elderly patients (n=56) and patients with AD (n=75) attending the Geriatric Rehabilitation Unit of Ankara Education and Research Hospital, Department of Physical Medicine and Rehabilitation were compared on several measures of disability including handgrip strength, knee x-rays graded for osteoarthritis, dual-energy x-ray absorptiometry results for osteoporosis, and depression scores in the training period of 2003-2004.

RESULTS: Handgrip strength values were significantly lower in patients with AD compared to the controls (19.4 versus 37 pounds force). Osteoporosis in the femoral neck was also more prominent in patients with AD compared to controls (T-scores: -2.1 versus -1.2). Handgrip strength was moderately correlated with femoral neck T-scores (r=0.6, p=0.001).

CONCLUSION: Strategies should be developed to protect patients with AD from osteoporosis and reduced muscle strength.

  • Copyright: © Neurosciences

Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Neurosciences Journal: 12 (2)
Neurosciences Journal
Vol. 12, Issue 2
1 Apr 2007
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Decreased handgrip strength and increased hip osteoporosis in patients with Alzheimer’s disease
Figen Ayhan, Feray Soyupek, Burak Tonuk, Figen Gokoglu, Rezan Yorgancioglu
Neurosciences Journal Apr 2007, 12 (2) 140-144;

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Decreased handgrip strength and increased hip osteoporosis in patients with Alzheimer’s disease
Figen Ayhan, Feray Soyupek, Burak Tonuk, Figen Gokoglu, Rezan Yorgancioglu
Neurosciences Journal Apr 2007, 12 (2) 140-144;
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© 2023 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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