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Research ArticleORIGINAL ARTICLES
Open Access

Rathke cleft cyst. MRI criteria for presumptive diagnosis

Santhosh Gaddikeri, Surjith Vattoth, Kristen O. Riley, George W. DeHoff, Charles B. Smith, Justin T. Combs and Glenn H. Roberson
Neurosciences Journal July 2013, 18 (3) 258-263;
Santhosh Gaddikeri
Department of Radiology, Neuroradiology Section, University Of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-6830, United States of America. Tel. +1 (205) 9343920. Fax. +1 (205) 9759262. E-mail: [email protected]
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Surjith Vattoth
Department of Radiology, Neuroradiology Section, University Of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-6830, United States of America. Tel. +1 (205) 9343920. Fax. +1 (205) 9759262. E-mail: [email protected]
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Kristen O. Riley
Department of Radiology, Neuroradiology Section, University Of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-6830, United States of America. Tel. +1 (205) 9343920. Fax. +1 (205) 9759262. E-mail: [email protected]
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George W. DeHoff
Department of Radiology, Neuroradiology Section, University Of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-6830, United States of America. Tel. +1 (205) 9343920. Fax. +1 (205) 9759262. E-mail: [email protected]
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Charles B. Smith
Department of Radiology, Neuroradiology Section, University Of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-6830, United States of America. Tel. +1 (205) 9343920. Fax. +1 (205) 9759262. E-mail: [email protected]
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Justin T. Combs
Department of Radiology, Neuroradiology Section, University Of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-6830, United States of America. Tel. +1 (205) 9343920. Fax. +1 (205) 9759262. E-mail: [email protected]
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Glenn H. Roberson
Department of Radiology, Neuroradiology Section, University Of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35249-6830, United States of America. Tel. +1 (205) 9343920. Fax. +1 (205) 9759262. E-mail: [email protected]
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Abstract

OBJECTIVE: To define MRI criteria for the presumptive diagnosis of Rathke cleft cyst (RCC).

METHODS: One hundred and three patient MRI scans suggesting RCC performed between January 2005 and January 2011 were retrospectively reviewed for indications, cyst location, T1 and T2 signal intensity, dimensions, encroachment on optic chiasm, enhancement pattern, and stability over a year.

RESULTS: Of the 103 patients analyzed, the suggestion of RCC was an incidental finding in 82.5% (n=85) of patients. Headache was the most common symptom in 11.6% (n=12), visual field deficit in 3.8% (n=4), and both headache and visual field deficit in 0.97% (n=1). The cyst was hyperintense on T1 in 55.3% (n=57), hypointense in 27.1% (n=28), and isointense in 17.4% (n=18). The cyst was T2 hyperintense in 57.2% (n=59), and iso-hypointense in 42.7% (n=54). The cyst showed no enhancement in 80.5% (n=83), and a thin marginal enhancement in 19.4% (n=20). The cyst showed a stable appearance in 99% (n=102) of patients after at least one year follow-up MRI study.

CONCLUSION: Rathke cleft cysts typically have a cystic appearance with T1 hyperintensity, sometimes with T1 iso- or hypointensity, variable T2 signal, and no or thin marginal enhancement and remain stable in size over time.

  • Copyright: © Neurosciences

Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Neurosciences Journal: 18 (3)
Neurosciences Journal
Vol. 18, Issue 3
1 Jul 2013
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Rathke cleft cyst. MRI criteria for presumptive diagnosis
Santhosh Gaddikeri, Surjith Vattoth, Kristen O. Riley, George W. DeHoff, Charles B. Smith, Justin T. Combs, Glenn H. Roberson
Neurosciences Journal Jul 2013, 18 (3) 258-263;

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Rathke cleft cyst. MRI criteria for presumptive diagnosis
Santhosh Gaddikeri, Surjith Vattoth, Kristen O. Riley, George W. DeHoff, Charles B. Smith, Justin T. Combs, Glenn H. Roberson
Neurosciences Journal Jul 2013, 18 (3) 258-263;
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© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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