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Review ArticleReview Article
Open Access

An overview of complications affecting the Central Nervous System following bariatric surgery

Azra Zafar and Ismail A. Khatri
Neurosciences Journal January 2018, 23 (1) 4-12; DOI: https://doi.org/10.17712/nsj.2018.1.20170316
Azra Zafar
From the Department of Neurology (Zafar), College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, King Fahd Hospital of the University, Alkhobar, Saudi Arabia, and from the Division of Neurology (Khatri), Department of Medicine, King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
FCPS Med, FCPS Neurology
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  • For correspondence: [email protected]
Ismail A. Khatri
From the Department of Neurology (Zafar), College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, King Fahd Hospital of the University, Alkhobar, Saudi Arabia, and from the Division of Neurology (Khatri), Department of Medicine, King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
MD, FAAN
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References

  1. ↵
    1. Lee EB,
    2. Mattson MP
    (2014) The neuropathology of obesity: insights from human disease. Acta Neuropathol 127, 3–28.
  2. ↵
    1. Obesity: preventing and managing the global epidemic
    (2000) Report of a WHO consultation. World Health Organ Tech Rep Ser 894, 1–253.
  3. ↵
    1. Stevens GA,
    2. Singh GM,
    3. Lu Y,
    4. Danaei G,
    5. Lin JK,
    6. Finucane MM,
    7. et al.
    (2012) National, regional, and global trends in adult overweight and obesity prevalences. Popul Health Metr 10, 22.
  4. ↵
    1. Poirier P,
    2. Cornier MA,
    3. Mazzone T,
    4. Stiles S,
    5. Cummings S,
    6. Klein S,
    7. et al.
    (2011) Bariatric surgery and cardiovascular risk factors: a scientific statement from the American Heart Association. Circulation 123, 1683–1701.
  5. ↵
    1. Finucane MM,
    2. Stevens GA,
    3. Cowan MJ,
    4. Danaei G,
    5. Lin JK,
    6. Paciorek CJ,
    7. et al.
    (2011) National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants. Lancet 377, 557–567.
  6. ↵
    1. Lavie CJ,
    2. Milani RV
    (2003) Obesity and cardiovascular disease: the hippocrates paradox? J Am Coll Cardiol 42, 677–679.
  7. ↵
    1. Lee EB
    (2011) Obesity, leptin, and Alzheimer's disease. Ann N Y Acad Sci 1243, 15–29.
    1. Debette S,
    2. Seshadri S,
    3. Beiser A,
    4. Au R,
    5. Himali JJ,
    6. Palumbo C,
    7. et al.
    (2011) Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline. Neurology 77, 461–468.
  8. ↵
    1. Doherty GH
    (2011) Obesity and the ageing brain: could leptin play a role in neurodegeneration? Curr Gerontol Geriatr Res 2011, 708154.
  9. ↵
    1. World Health Organization
    (2017) Obesity and overweight (Geneva (CH)) Available from: http://www.who.int/mediacentre/factsheets/fs311/en/.
  10. ↵
    1. Dubnov-Raz G,
    2. Berry EM
    (2011) The dietary treatment of obesity. Med Clin North Am 95, 939–952.
  11. ↵
    1. Buchwald H,
    2. Oien DM
    (2013) Metabolic/bariatric surgery worldwide 2011. Obes Surg 23, 427–36.
  12. ↵
    1. Espinet-Coll E,
    2. Nebreda-Durán J,
    3. Gómez-Valero JA,
    4. Muñoz-Navas M,
    5. Pujol-Gebelli J,
    6. Vila-Lolo C,
    7. et al.
    (2012) Current endoscopic techniques in the treatment of obesity. Rev Esp Enferm Dig 104, 72–87.
  13. ↵
    1. Park CW,
    2. Torquati A
    (2011) Physiology of weight loss surgery. Surg Clin North Am 91, 1149–1161.
  14. ↵
    1. Smith BR,
    2. Schauer P,
    3. Nguyen NT
    (2011) Surgical approaches to the treatment of obesity: bariatric surgery. Med Clin North Am 95, 1009–1030.
  15. ↵
    1. Sjöström L,
    2. Peltonen M,
    3. Jacobson P,
    4. Sjöström CD,
    5. Karason K,
    6. Wedel H,
    7. et al.
    (2012) Bariatric surgery and long-term cardiovascular events. JAMA 307, 56–65.
  16. ↵
    1. Sjöström L,
    2. Gummesson A,
    3. Sjöström CD,
    4. Narbro K,
    5. Peltonen M,
    6. Wedel H,
    7. et al.
    (2009) Swedish Obese Subjects Study. Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial. Lancet Oncol 10, 653–662.
  17. ↵
    1. Christou NV,
    2. Lieberman M,
    3. Sampalis F,
    4. Sampalis JS
    (2008) Bariatric surgery reduces cancer risk in morbidly obese patients. Surg Obes Relat Dis 4, 691–695.
  18. ↵
    1. Christou NV,
    2. Sampalis JS,
    3. Liberman M,
    4. Look D,
    5. Auger S,
    6. McLean AP,
    7. et al.
    (2004) Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients. Ann Surg 240, 416–423.
  19. ↵
    1. Coblijn UK,
    2. Karres J,
    3. de Raaff CA,
    4. de Castro SM,
    5. Lagarde SM,
    6. van Tets WF,
    7. et al.
    (2017) Predicting postoperative complications after bariatric surgery: the Bariatric Surgery Index for Complications, BASIC. Surg Endosc 31, 4438–4445.
  20. ↵
    1. Encinosa WE,
    2. Bernard DM,
    3. Du D,
    4. Steiner CA
    (2009) Recent improvements in bariatric surgery outcomes. Med Care 47, 531–535.
  21. ↵
    1. Buchwald H,
    2. Estok R,
    3. Fahrbach K,
    4. Banel D,
    5. Sledge I
    (2007) Trends in mortality in bariatric surgery: a systematic review and meta-analysis. Surgery 142, 621–632.
  22. ↵
    1. Longitudinal Assessment of Bariatric Surgery (LABS) Consortium,
    2. Flum DR,
    3. Belle SH,
    4. King WC,
    5. Wahed AS,
    6. Berk P,
    7. et al.
    (2009) Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med 361, 445–454.
  23. ↵
    1. Smith MD,
    2. Patterson E,
    3. Wahed AS,
    4. Belle SH,
    5. Berk PD,
    6. Courcoulas AP,
    7. et al.
    (2011) Thirty-day mortality after bariatric surgery: independently adjudicated causes of death in the longitudinal assessment of bariatric surgery. Obes Surg 21, 1687–1692.
  24. ↵
    1. Ziegler O,
    2. Sirveaux MA,
    3. Brunaud L,
    4. Reibel N,
    5. Quilliot D
    (2009) Medical follow up after bariatric surgery: nutritional and drug issues. General recommendations for the prevention and treatment of nutritional deficiencies. Diabetes Metab 35, 544–557.
  25. ↵
    1. Tack J,
    2. Deloose E
    (2014) Complications of bariatric surgery: dumping syndrome, reflux and vitamin deficiencies. Best Pract Res Clin Gastroenterol 28, 741–749.
  26. ↵
    1. Berger JR
    (2004) The neurological complications of bariatric surgery. Arch Neurol 61, 1185–1189.
  27. ↵
    1. Alqahtani HA,
    2. Khan AS,
    3. Khan MA,
    4. Aldarmahi AA,
    5. Lodhi Y
    (2016) Neurological complications of bariatric surgery. Neuroscience (Riyadh) 21, 241–245.
  28. ↵
    1. Tabbara M,
    2. Carandina S,
    3. Bossi M,
    4. Polliand C,
    5. Genser L,
    6. Barrat C
    (2016) Rare neurological complications after sleeve gastrostomy. Obesity Surg 26, 2843–2848.
  29. ↵
    1. Juhasz-Pocsine K,
    2. Rudnicki SA,
    3. Archer RL,
    4. Harik SI
    (2007) Neurologic complications of gastric bypass surgery for morbid obesity. Neurology 68, 1843–1850.
  30. ↵
    1. Frantz DJ
    (2012) Neurologic complications of bariatric surgery: involvement of central, peripheral, and enteric nervous systems. Curr Gastroenterol Rep 14, 367–372.
  31. ↵
    1. Kumar N
    (2014) Neurologic complications of bariatric surgery. Continuum (Minneap Minn) 20, 580–597.
  32. ↵
    1. Kopelman MD
    (1995) The Korsakoff syndrome. Br J Psychiatry 166, 154–173.
  33. ↵
    1. Abarbanel JM,
    2. Berginer VM,
    3. Osimani A,
    4. Solomon H,
    5. Charuzi I
    (1987) Neurologic complications after gastric restriction surgery for morbid obesity. Neurology 37, 196–200.
  34. ↵
    1. Singh S,
    2. Kumar A
    (2007) Wernicke encephalopathy after obesity surgery: a systematic review. Neurology 68, 807–811.
  35. ↵
    1. Aasheim ET
    (2008) Wernicke encephalopathy after bariatric surgery: a systematic review. Ann Surg 248, 714–720.
  36. ↵
    1. Stroh C,
    2. Meyer F,
    3. Manger T
    (2014) Beriberi, a severe complication after metabolic surgery - review of the literature. Obes Facts 7, 246–252.
  37. ↵
    1. Kühn AL,
    2. Hertel F,
    3. Boulanger T,
    4. Diederich NJ
    (2012) Vitamin B1 in the treatment of Wernicke's encephalopathy due to hyperemesis after gastroplasty. J Clin Neurosci 19, 1303–1305.
  38. ↵
    1. Traube M,
    2. Bock JL,
    3. Boyer JL
    (1983) D-Lactic acidosis after jejunoileal bypass: identification of organic anions by nuclear magnetic resonance spectroscopy. Ann Intern Med 98, 171–3.
  39. ↵
    1. Dahlquist NR,
    2. Perrault J,
    3. Callaway CW,
    4. Jones JD
    (1984) D-Lactic acidosis and encephalopathy after jejunoileostomy: response to overfeeding and to fasting in humans. Mayo Clin Proc 59, 141–145.
    1. Thurn JR,
    2. Pierpont GL,
    3. Ludvigsen CW,
    4. Eckfeldt JH
    (1985) D-lactate encephalopathy. Am J Med 79, 717–721.
  40. ↵
    1. Narula RK,
    2. El Shafei A,
    3. Ramaiah D,
    4. Schmitz PG
    (2000) D-lactic acidosis 23 years after jejuno-ileal bypass. Am J Kidney Dis 36, E9.
  41. ↵
    1. Fabian E,
    2. Kramer L,
    3. Siebert F,
    4. Högenauer C,
    5. Raggam RB,
    6. Wenzl H,
    7. et al.
    (2017) D-lactic acidosis - case report and review of the literature. Z Gastroenterol 55, 75–82.
  42. ↵
    1. Naqarur A,
    2. Fenves AZ
    (2017) Late presentation of fatal hyperammonemic encephalopathy after Roux-en-Y gastric bypass. Proc (Bayl Univ Med Cent) 30, 41–43.
  43. ↵
    1. Hu WT,
    2. Kantarci OH,
    3. Merritt JL 2nd.,
    4. McGrann P,
    5. Dyck PJ,
    6. Lucchinetti CF,
    7. et al.
    (2007) Ornithine transcarbamylase deficiency presenting as encephalopathy during adulthood following bariatric surgery. Arch Neurol 64, 126–128.
    1. Kromas ML,
    2. Mousa OY,
    3. John S
    (2015) Hyperammonemia-induced encephalopathy: A rare devastating complication of bariatric surgery. World J Hepatol 7, 1007–1111.
  44. ↵
    1. Acharya G,
    2. Mehra S,
    3. Patel R,
    4. Frunza-Stefan S,
    5. Kaur H
    (2016) Fatal Nonhepatic Hyperammonemia in ICU Setting: A Rare but Serious Complication following Bariatric Surgery. Case Rep Crit Care 2016, 8531591.
  45. ↵
    1. Fenves AZ,
    2. Shchelochkov OA,
    3. Mehta A
    (2015) Hyperammonemic syndrome after Roux-en-Y gastric bypass. Obesity (Silver Spring) 23, 746–749.
  46. ↵
    1. Estrella J,
    2. Yee G,
    3. Wilcken B,
    4. Tchan M,
    5. Talbot M
    (2014) Hyperammonemic encephalopathy complicating bariatric surgery: a case study and review of the literature. Surg Obes Relat Dis 10, e35–e38.
  47. ↵
    1. Kalarchian MA,
    2. Marcus MD,
    3. Levine MD,
    4. Courcoulas AP,
    5. Pilkonis PA,
    6. Ringham RM,
    7. et al.
    (2007) Psychiatric disorders among bariatric surgery candidates: relationship to obesity and functional health status. Am J Psychiatry 164, 328–334.
  48. ↵
    1. Faulconbridge LF,
    2. Wadden TA,
    3. Thomas JG,
    4. Jones-Corneille LR,
    5. Sarwer DB,
    6. Fabricatore AN
    (2013) Changes in depression and quality of life in obese individuals with binge eating disorder: bariatric surgery versus lifestyle modification. Surg Obes Relat Dis 9, 790–796.
  49. ↵
    1. Burgmer R,
    2. Legenbauer T,
    3. Müller A,
    4. de Zwaan M,
    5. Fischer C,
    6. Herpertz S
    (2014) Psychological outcome 4 years after restrictive bariatric surgery. Obes Surg 24, 1670–1678.
  50. ↵
    1. Marcus MD,
    2. Kalarchian MA,
    3. Courcoulas AP
    (2009) Psychiatric evaluation and follow-up of bariatric surgery patients. Am J Psychiatry 166, 285–291.
  51. ↵
    1. de Zwaan M,
    2. Marschollek M,
    3. Allison KC
    (2015) The Night Eating Syndrome (NES) in Bariatric Surgery Patients. Eur Eat Disord Rev 23, 426–234.
  52. ↵
    1. King WC,
    2. Chen JY,
    3. Mitchell JE,
    4. Kalarchian MA,
    5. Steffen KJ,
    6. Engel SG,
    7. et al.
    (2012) Prevalence of alcohol use disorders before and after bariatric surgery. JAMA 307, 2516–2525.
  53. ↵
    1. Tindle HA,
    2. Omalu B,
    3. Courcoulas A,
    4. Marcus A,
    5. Hammers J,
    6. Kuller LH
    (2010) Risk of suicide after long term follow up from bariatric surgery. Am J Med 123, 1036–1042.
  54. ↵
    1. Peterhänsel C,
    2. Petroff D,
    3. Klinitzke G,
    4. Kersting A,
    5. Wagner B
    (2013) Risk of completed suicide after bariatric surgery: a systematic review. Obes Rev 14, 369–382.
  55. ↵
    1. Nepal H,
    2. Bhattarai M,
    3. Agustin ET
    (2015) New onset mania following bariatric surgery. Psychiatry Investig 12, 152–154.
  56. ↵
    1. Yen YC,
    2. Huang CK,
    3. Tai CM
    (2014) Psychiatric aspects of bariatric surgery. Curr Opin Psychiatry 27, 374–379.
  57. ↵
    1. Choi JY,
    2. Scarborough TK
    (2004) Stroke and seizure following a recent laparoscopic Roux-en-Y gastric bypass. Obes Surg 14, 857–860.
  58. ↵
    1. Fragoso YD,
    2. Alves-Leon SV,
    3. Anacleto Ade C,
    4. Brooks JB,
    5. Gama PD,
    6. Gomes S,
    7. et al.
    (2012) Neurological complications following bariatric surgery. Arq Neuropsiquiatr 70, 700–703.
  59. ↵
    1. Falah M,
    2. Al-Ghawi E,
    3. Adnan R,
    4. Al-Sarawi A,
    5. Al-Harbi T
    (2016) Neurological complications of bariatric surgery: A review of 15 patients (P3.380). Neurology 86, 380.
  60. ↵
    1. Anstey KJ,
    2. Cherbuin N,
    3. Budge M,
    4. Young J
    (2011) Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies. Obes Rev 12, e426–e437.
  61. ↵
    1. Blanco-Gómez A,
    2. Ferré N,
    3. Luque V,
    4. Cardona M,
    5. Gispert-Llauradó M,
    6. Escribano J,
    7. et al.
    (2015) Being overweight or obese is associated with inhibition control in children from six to ten years of age. Acta Paediatr 104, 619–625.
  62. ↵
    1. Alosco ML,
    2. Galioto R,
    3. Spitznagel MB,
    4. Strain G,
    5. Devlin M,
    6. Cohen R,
    7. et al.
    (2014) Cognitive function after bariatric surgery: evidence for improvement 3 years after surgery. Am J Surg 207, 870–876.
    1. Miller LA,
    2. Crosby RD,
    3. Galioto R,
    4. Strain G,
    5. Devlin MJ,
    6. Wing R,
    7. et al.
    (2013) Bariatric surgery patients exhibit improved memory function 12 months postoperatively. Obes Surg 23, 1527–1535.
  63. ↵
    1. Spitznagel MB,
    2. Hawkins M,
    3. Alosco M,
    4. Galioto R,
    5. Garcia S,
    6. Miller L,
    7. et al.
    (2015) Neurocognitive Effects of Obesity and Bariatric Surgery. Eur Eat Disord Rev 23, 488–495.
  64. ↵
    1. Graff-Radford J,
    2. Whitwell JL,
    3. Trenerry MR,
    4. Ahlskog JE,
    5. Jensen MD,
    6. Jack CR Jr.,
    7. et al.
    (2011) Focal brain atrophy in gastric bypass patients with cognitive complaints. J Clin Neurosci 18, 1671–1676.
  65. ↵
    1. Schievink WI,
    2. Goseland A,
    3. Cunneen S
    (2014) Bariatric surgery as a possible risk factor for spontaneous intracranial hypotension. Neurology 83, 1819–1822.
  66. ↵
    1. Kumar N,
    2. Ahlskog JE,
    3. Gross JB Jr.
    (2004) Acquired hypocupremia after gastric surgery. Clin Gastroenterol Hepatol 2, 1074–1079.
  67. ↵
    1. Kazemi A,
    2. Frazier T,
    3. Cave M
    (2010) Micronutrient-related neurologic complications following bariatric surgery. Curr Gastroenterol Rep 12, 288–295.
  68. ↵
    1. Koffman BM,
    2. Greenfield LJ,
    3. Ali II,
    4. Pirzada NA
    (2006) Neurologic complications after surgery for obesity. Muscle Nerve 33, 166–176.
  69. ↵
    1. Becker DA,
    2. Bacler LJ,
    3. Galetta SL
    (2012) The Neurological Complications of Nutritional Deficiency following Bariatric Surgery. J Obes 2012, 608534.
  70. ↵
    1. Martana MR,
    2. Davis WE
    (2009) Vitamin deficiency after gastric bypass surgery: a review. South Med J 102, 1025–1031.
  71. ↵
    1. Naismith RT,
    2. Shepherd JB,
    3. Weihl CC,
    4. Tutlam NT,
    5. Cross AH
    (2009) Acute and bilateral blindness due to optic neuropathy associated with copper deficiency. Arch Neurol 66, 1025–1027.
  72. ↵
    1. Fok JS,
    2. Li JY,
    3. Yong TY
    (2012) Visual deterioration caused by vitamin A deficiency in patients after bariatric surgery. Eat Weight Disord 17, e144–e146.
  73. ↵
    1. Ramos-Leví AM,
    2. Sánchez-Pernaute A,
    3. Rubio Herrera MA
    (2013) Dermatitis and optic neuropathy due to zinc deficiency after malabsortive bariatric surgery. Nutr Hosp 28, 1345–1347.
  74. ↵
    1. Neff KJ,
    2. Olbers T,
    3. Le Roux CW
    (2013) Bariatric surgery: the challenges with candidate selection, individualizing treatment and clinical outcomes. BMC Med 11, 8.
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An overview of complications affecting the Central Nervous System following bariatric surgery
Azra Zafar, Ismail A. Khatri
Neurosciences Journal Jan 2018, 23 (1) 4-12; DOI: 10.17712/nsj.2018.1.20170316

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An overview of complications affecting the Central Nervous System following bariatric surgery
Azra Zafar, Ismail A. Khatri
Neurosciences Journal Jan 2018, 23 (1) 4-12; DOI: 10.17712/nsj.2018.1.20170316
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