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Research ArticleOriginal Articles
Open Access

Prescribing practices in the treatment of depression among psychiatrists in Oman

Marwa A. Albalushi, Mandhar. H Almaqbali, Salim K. Al-Huseini and Hamed N. Alsinawi
Neurosciences Journal April 2021, 26 (2) 152-157; DOI: https://doi.org/10.17712/nsj.2021.2.20200110
Marwa A. Albalushi
From the Department of Psychiatry (Al-Balushi, AlMaqbali), Sohar Hospital, Sohar, Department of Behavioral Medicine (AlSinawi), College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Ministry of Health (Al-Huseini), Oman
MD, OMSBpsych
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Mandhar. H Almaqbali
From the Department of Psychiatry (Al-Balushi, AlMaqbali), Sohar Hospital, Sohar, Department of Behavioral Medicine (AlSinawi), College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Ministry of Health (Al-Huseini), Oman
MD, OMSBpsych
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  • For correspondence: [email protected]
Salim K. Al-Huseini
From the Department of Psychiatry (Al-Balushi, AlMaqbali), Sohar Hospital, Sohar, Department of Behavioral Medicine (AlSinawi), College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Ministry of Health (Al-Huseini), Oman
MD, OMSBpsych
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Hamed N. Alsinawi
From the Department of Psychiatry (Al-Balushi, AlMaqbali), Sohar Hospital, Sohar, Department of Behavioral Medicine (AlSinawi), College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Ministry of Health (Al-Huseini), Oman
MD, FRCPsych
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    Figure 1

    - Participants’ responses regarding the side effects of antidepressant and the most likely associated agent. *Others include antidepressants listed in the Massachusetts General Hospital Psychopharmacology questionnaire but were not mentioned in the table.

Tables

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    Table 1

    - Participants’ choice of preferred antidepressant agents in various clinical scenarios and depression subtypes.

    Clinical scenario or depression subtypePreferred agent (%)
    Anxious depressionSSRIs (64.1)
    Depression with prominent insomniaMirtazapine (75.0)
    Depression with atypical featuresMAOIs (42.3)
    Depression with melancholic featuresSSRIs (39.7)

    MAOIs - Monaoamine Oxidase Inhibitors, SSRIs - Selective Serotonin Reuptake Inhibitors

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      Table 2

      - Summary of Peterson’s study results versus the current empirical evidence.

      Peterson's study results (percentage of participants' preference of antidepressant treatment)Evidence (APA Guidelines 2000, revised)
      EfficacySSRIs (48%)No difference
      Sexual dysfunctionFluoxetine (56%)More common with paroxetine
      AgitationFluoxetine (52%)Comparable to other SSRIs
      Discontinuation syndromeParoxetine (47%)Occurs among short half-life antidepressants
      Atypical depressionSSRIs (57%)MAOIs
      Melancholic depressionSSRIs (57%)No specific recommendation, (pharmacotherapy and ECT leads to good responses)

      APA - American Psychiatric Association, ECT - electric shock treatment, MAOIs - Monaoamine Oxidase Inhibitors, SSRIs - Selective Serotonin Reuptake Inhibitors

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      Neurosciences Journal: 26 (2)
      Neurosciences Journal
      Vol. 26, Issue 2
      1 Apr 2021
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      Prescribing practices in the treatment of depression among psychiatrists in Oman
      Marwa A. Albalushi, Mandhar. H Almaqbali, Salim K. Al-Huseini, Hamed N. Alsinawi
      Neurosciences Journal Apr 2021, 26 (2) 152-157; DOI: 10.17712/nsj.2021.2.20200110

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      Prescribing practices in the treatment of depression among psychiatrists in Oman
      Marwa A. Albalushi, Mandhar. H Almaqbali, Salim K. Al-Huseini, Hamed N. Alsinawi
      Neurosciences Journal Apr 2021, 26 (2) 152-157; DOI: 10.17712/nsj.2021.2.20200110
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