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Research ArticleORIGINAL ARTICLES
Open Access

Cytogenetics study in severely mentally retarded patients

Akeel A. Yasseen and Thekra A. Al-Musawi
Neurosciences Journal July 2001, 6 (3) 156-161;
Akeel A. Yasseen
Medical Genetics, Department of Pathology and Forensic Medicine, College of Medicine, Kufa University, PO Box 18, Kufa, Iraq. Fax +964 (1) 886 7170.
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Thekra A. Al-Musawi
Department of Pathology and Forensic Medicine, College of Medicine, Kufa University, Kufa, Iraq.
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Abstract

OBJECTIVE: To study the frequency of chromosomal abnormalities in severely mentally retarded Iraqi patients. Secondly, to determine the types of chromosomal abnormalities that play a major role in the causation of mental retardation and to compare our results with those reported elsewhere.

METHODS: Twenty-one patients with severe mental retardation were subject to chromosomal analysis. The lymphocyte culture was carried out according to standard methods.

RESULTS: Fourteen of the subjected mentally retarded patients had chromosomal abnormalities, 13 autosomal abnormalities, and only one had sex chromosomal abnormalities. However, structural autosomes were found to be the most prominent abnormalities and only 2 patients were demonstrated to have diagnosable syndrome.

CONCLUSION: Chromosomal abnormalities are an important cause of mental retardation and its frequency increased with the severity of mental retardation. We concluded that chromosomal studies in mentally retarded patients help in accurate diagnosis and proper prognosis followed by genetic counseling and management rehabilitation.

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Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Neurosciences Journal: 6 (3)
Neurosciences Journal
Vol. 6, Issue 3
1 Jul 2001
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Cytogenetics study in severely mentally retarded patients
Akeel A. Yasseen, Thekra A. Al-Musawi
Neurosciences Journal Jul 2001, 6 (3) 156-161;

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Cytogenetics study in severely mentally retarded patients
Akeel A. Yasseen, Thekra A. Al-Musawi
Neurosciences Journal Jul 2001, 6 (3) 156-161;
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© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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