Quantitative analysis of myelinated axons of commissural fibers in the cat brain

OBJECTIVE: There are limited data related to the number of commissural axons found in various species. Although the corpus callosum has been investigated in cat, there are no data on the number of its myelinated axons. Additionally, the number of myelinated axons of anterior, posterior and habenular commissures are not documented for the cat. Therefore, we aimed to examine the topographic distribution and regional numerical differences of myelinated axons in encephalic commissures of the cat.

METHODS: This study was carried out at the Faculty of Medicine, Hacettepe University, Ankara, Turkey, from March 2003 to July 2003. The myelinated axons of the encephalic commissures of one cat were counted in this study.

RESULTS: In parts of the corpus callosum, a statistically significant difference was found between rostrum and genu, rostrum and truncus, genu and truncus, genu and splenium and truncus and splenium. However, no statistically significant difference was found between rostrum and splenium. When comparing the number of myelinated axons of anterior, posterior and habenular commissures, statistically significant differences were found between anterior and habenular commissures, and between posterior and habenular commissures. No statistically significant difference was found between anterior and posterior commissures.

CONCLUSION: These numerical data, evaluated by quantitative analytical statistical methods, might be useful in filling the lack of information on the mean numbers of myelinated axons of different commissures. Knowledge of the number of myelinated axons in different parts of the corpus callosum may also be very important when performing surgical procedures of the corpus callosum, such as commissurectomies.