[HTML][HTML] miRNAs: biological and clinical determinants in epilepsy

WA Alsharafi, B Xiao, MM Abuhamed… - Frontiers in molecular …, 2015 - frontiersin.org
Recently, microRNAs (miRNAs) are reported to be crucial modulators in the pathogenesis
and potential treatment of epilepsies. To date, several miRNAs have been demonstrated to be …

[HTML][HTML] Correlation between IL-10 and microRNA-187 expression in epileptic rat hippocampus and patients with temporal lobe epilepsy

WA Alsharafi, B Xiao, MM Abuhamed, FF Bi… - Frontiers in Cellular …, 2015 - frontiersin.org
Accumulating evidence is emerging that microRNAs (miRNAs) are key regulators in controlling
neuroinflammatory responses that are known to play a potential role in the pathogenesis …

Selective Loss and Axonal Sprouting of GABAergic Interneurons in the Sclerotic Hippocampus Induced by LiCl–Pilocarpine

…, L Feng, F Yi, G Li, S Li, MA Mutasem… - International Journal …, 2011 - Taylor & Francis
In this study, we performed immunohistochemistry for somatostatin (SS), neuropeptide Y (NPY),
and parvalbumin (PV) in LiCl–pilocarpine-treated rats to observe quantitative changes …

Changes in the numbers and distribution of calretinin in the epileptic rat hippocampus

MM Abuhamed, X Bo, WA Alsharafi, L Jing… - Neurosciences …, 2010 - nsj.org.sa
OBJECTIVE: To examine calretinin (CR)-containing interneurons that degenerate in the
hippocampus in post status epilepticus (SE) rats at different time points. METHODS: This study …

Neuronal synaptic reconstruction in hippocampus in chronic phase of pilocarpine-treated rats

F Yi, MM Abuhamed, LL Long, Y Li, SY Li… - Zhonghua yi xue za …, 2011 - europepmc.org
Objective To explore the aberrant formation of excitatory and inhibitory circuit rearrangements
of hippocampus in temporal lobe epilepsy. Methods Pilocarpine-induced animal model …

Comparison between solitary and multiple intracranial tuberculoma

MM Abuhamed, X Bo, L Xiaoqin, Z Fufeng, L Long… - Neurosciences …, 2009 - nsj.org.sa
OBJECTIVE: To compare and analyze the clinical, radiological, and pathological features of
solitary or/and multiple CNS tuberculomas (CNSTs). METHODS: The study was conducted …

Experimental epileptic discharge can be transmitted between 2 brains in rats

MM Abuhamed, X Bo, S Zhi - Neurosciences Journal, 2009 - nsj.org.sa
OBJECTIVE: To identify whether epileptic discharges can be conducted out of the brain
according to the principle of a lightning rod. METHODS: This experimental study was conducted …

Use of urokinase in the treatment of tuberculous meningitis hydrocephalus

MM Abuhamed, S Zhi, X Bo - Neurosciences Journal, 2009 - nsj.org.sa
We present a patient with hydrocephalus after tuberculous meningitis successfully treated
with urokinase. She presented with multiple episodes of headache, fever, and vomiting. She …

Mutation analysis of WASF2 and GALE genes in one Chinese family with benign familial infantile convulsions with a novel locus

Z Xiaohong, M Abuhamed… - Journal of Investigative …, 2007 - journals.sagepub.com
<p>Benign familial infantile convulsions (BFIC) are an autosomal dominant form of idiopathic
epilepsy in which partial and generalized seizures commence in the first 3 months of life …

Use of urokinase in the treatment of tuberculous meningitis hydrocephalus

A Mutasem M, Z Song, B Xiao - 2009 - pesquisa.bvsalud.org
We present a patient with hydrocephalus after tuberculous meningitis successfully treated
with urokinase. She presented with multiple episodes of headache, fever, and vomiting. She …