Neurosarcoidosis presenting with persistent vomiting

Abstract

Sarcoidosis is a multi-system granulomatous disease of unknown etiology. It mainly affects the lungs more than other organs, but liver, skin, lymph nodes, and nervous system can be involved. The last is referred to as neurosarcoidosis with a wide range of clinical manifestations depending on the area of the nervous system involved. The differential diagnosis is wide, and the diagnosis, which is based on the histopathology, is sometimes difficult to confirm. Magnetic resonance imaging is the imaging modality of choice for establishing CNS involvement along with the clinical presentation. Cerebrospinal fluid analysis is indicative of the disease activity. We report a 39-year-old man of Indian origin who presented with persistent vomiting for over 2 years due to hypopituitarism and active neurosarcoidosis.