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Research ArticleOriginal Article
Open Access

Prevalence of factors associated with poor outcomes of hospitalized myasthenia gravis patients in Thailand

Somsak Tiamkao, Sineenard Pranboon, Kaewjai Thepsuthammarat and Kittisak Sawanyawisuth
Neurosciences Journal October 2014, 19 (4) 286-290;
Somsak Tiamkao
From the Department of Medicine (Tiamkao, Sawanyawisuth), the Clinical Epidemiology Unit (Thepsuthammarat), Faculty of Medicine, the Nursing Division (Pranboon), Srinagarind Hospital, the Integrated Epilepsy Research Group (Tiamkao, Pranboon), the North-Eastern Stroke Research Group (Tiamkao), and the Research Center in Back, Neck Other Joint Pain and Human Performance (Sawanyawisuth), Khon Kaen University, Khon Kaen, Thailand
MD
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  • For correspondence: [email protected]
Sineenard Pranboon
From the Department of Medicine (Tiamkao, Sawanyawisuth), the Clinical Epidemiology Unit (Thepsuthammarat), Faculty of Medicine, the Nursing Division (Pranboon), Srinagarind Hospital, the Integrated Epilepsy Research Group (Tiamkao, Pranboon), the North-Eastern Stroke Research Group (Tiamkao), and the Research Center in Back, Neck Other Joint Pain and Human Performance (Sawanyawisuth), Khon Kaen University, Khon Kaen, Thailand
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Kaewjai Thepsuthammarat
From the Department of Medicine (Tiamkao, Sawanyawisuth), the Clinical Epidemiology Unit (Thepsuthammarat), Faculty of Medicine, the Nursing Division (Pranboon), Srinagarind Hospital, the Integrated Epilepsy Research Group (Tiamkao, Pranboon), the North-Eastern Stroke Research Group (Tiamkao), and the Research Center in Back, Neck Other Joint Pain and Human Performance (Sawanyawisuth), Khon Kaen University, Khon Kaen, Thailand
PhD
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Kittisak Sawanyawisuth
From the Department of Medicine (Tiamkao, Sawanyawisuth), the Clinical Epidemiology Unit (Thepsuthammarat), Faculty of Medicine, the Nursing Division (Pranboon), Srinagarind Hospital, the Integrated Epilepsy Research Group (Tiamkao, Pranboon), the North-Eastern Stroke Research Group (Tiamkao), and the Research Center in Back, Neck Other Joint Pain and Human Performance (Sawanyawisuth), Khon Kaen University, Khon Kaen, Thailand
MD, PhD
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Article Figures & Data

Tables

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    Table 1

    Prevalence rate of hospitalized myasthenia gravis patients classified by regions of Thailand.

    RegionsPopulation ages 18 and overNumber of admissions by primary diagnosis (G70)
    NumberPatient/100,000
    Northern8,871,7052202.48
    Northeast15,964,9362761.73
    Central11,896,5553913.39
    Southern6,287,474490.78
    Total43,020,6709362.17
      • View popup
      Table 2

      Factors affecting discharge status of hospitalized myasthenia gravis patients (N=936).

      VariableDischarge StatusP-value
      ImprovedNot improvedDeadTotal
      n (%)
      Gender0.399
       Male242 (91.0)21 (7.9)3 (1.1)266 (28.4)
       Female603 (90.0)50 (7.5)17 (2.5)670 (71.6)
      Age0.072
       18-29138 (91.4)12 (7.9)1 (0.7)151 (16.1)
       30-39201 (91.8)16 (7.3)2 (0.9)219 (23.4)
       40-49204 (89.1)22 (9.6)3 (1.3)229 (24.5)
       50-59177 (90.3)14 (7.1)5 (2.6)196 (20.9)
       60-6993 (89.4)5 (4.8)6 (5.8)104 (11.1)
       70-7923 (88.5)1 (3.8)2 (7.7)26 (2.8)
       80+9 (81.8)1 (9.1)1 (9.1)11 (1.2)
      Insurance groups0.040
       Government welfare95 (90.5)6 (5.7)4 (3.8)105 (11.2)
       Social welfare183 (95.3)7 (3.6)2 (1.0)192 (20.5)
       Universal coverage567 (88.7)58 (9.1)14 (2.2)639 (68.3)
      Hospital category<0.001
       Primary72 (72.0)27 (27.0)1 (1.0)100 (11.0)
       Secondary175 (87.1)22 (10.9)4 (2.0)201 (21.0)
       Tertiary491 (94.2)18 (3.5)12 (2.3)521 (56.0)
       Private107 (93.9)4 (3.5)3 (2.6)114 (12.0)
      Regions<0.001
       Northern197 (89.5)19 (8.6)4 (1.8)220 (23.5)
       Northeast240 (87.0)34 (12.3)2 (0.7)276 (29.5)
       Central367 (93.9)11 (2.8)13 (3.3)391 (41.8)
       Southern41 (83.7)7 (14.3)1 (2.0)49 (5.2)
      Pneumonia<0.001
       No778 (92.0)56 (6.6)12 (1.4)846 (90.4)
       Yes67 (74.4)15 (16.7)8 (8.9)90 (9.6)
      Respiratory failure<0.001
       No660 (94.0)41 (5.8)1 (0.1)702 (75.0)
       Yes185 (79.1)30 (12.8)19 (8.1)234 (25.0)
      Intravenous immunoglobins0.999
       No840 (90.2)71 (7.6)20 (2.1)931 (99.5)
       Yes5 (100.0)0 (0.0)0 (0.0)5 (0.5)
      • View popup
      Table 3

      Length of stay of hospitalized myasthenia gravis patients by various factors.

      FactorsCountLength of stayP-value
      MeanSD
      Pneumonia<0.001
       No8468.5014.31
       Yes9028.7434.59
      Respiratory failure<0.001
       No7026.3510.22
       Yes23422.7428.74
      IVIG treatment23422.7428.740.142
       No23022.3028.35
       Yes448.0044.12
        • View popup
        Table 4

        Significant factors associated with poor outcome at discharge of hospitalized myasthenia gravis patients by multivariate logistic analysis.

        VariableAdjusted odds ratio95% confidence intervalP-value
        Hospital category<0.001
         Primary1.00
         Secondary0.240.12-0.46
         Tertiary0.090.04-0.18
         Private0.280.09-0.84
        Pneumonia0.027
         No1.00
         Yes2.201.10-4.39
        Respiratory failure<0.001
         No1.00<0.001
         Yes4.672.66-8.21
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        Neurosciences Journal: 19 (4)
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        1 Oct 2014
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        Prevalence of factors associated with poor outcomes of hospitalized myasthenia gravis patients in Thailand
        Somsak Tiamkao, Sineenard Pranboon, Kaewjai Thepsuthammarat, Kittisak Sawanyawisuth
        Neurosciences Journal Oct 2014, 19 (4) 286-290;

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        Prevalence of factors associated with poor outcomes of hospitalized myasthenia gravis patients in Thailand
        Somsak Tiamkao, Sineenard Pranboon, Kaewjai Thepsuthammarat, Kittisak Sawanyawisuth
        Neurosciences Journal Oct 2014, 19 (4) 286-290;
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