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Brief ReportBrief Communication
Open Access

Neurological manifestations, laboratory and neuroimaging features in HIV-infected patients

Hai Chen, Fangju Lin, Shimeng Liu, Yuwei Da and Dongmei Guo
Neurosciences Journal October 2017, 22 (4) 311-315; DOI: https://doi.org/10.17712/nsj.2017.4.20160606
Hai Chen
From the Department of Neurology (Chen, Liu, Da, Guo), Xuanwu Hospital of Capital Medical University, and from Department of Neurology (Lin), Beijing Shijingshan Hospital, Capital Medical University Beijing, People’s Republic of China
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Fangju Lin
From the Department of Neurology (Chen, Liu, Da, Guo), Xuanwu Hospital of Capital Medical University, and from Department of Neurology (Lin), Beijing Shijingshan Hospital, Capital Medical University Beijing, People’s Republic of China
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Shimeng Liu
From the Department of Neurology (Chen, Liu, Da, Guo), Xuanwu Hospital of Capital Medical University, and from Department of Neurology (Lin), Beijing Shijingshan Hospital, Capital Medical University Beijing, People’s Republic of China
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Yuwei Da
From the Department of Neurology (Chen, Liu, Da, Guo), Xuanwu Hospital of Capital Medical University, and from Department of Neurology (Lin), Beijing Shijingshan Hospital, Capital Medical University Beijing, People’s Republic of China
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Dongmei Guo
From the Department of Neurology (Chen, Liu, Da, Guo), Xuanwu Hospital of Capital Medical University, and from Department of Neurology (Lin), Beijing Shijingshan Hospital, Capital Medical University Beijing, People’s Republic of China
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  • For correspondence: [email protected]
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    Figure 1

    Magnetic Resonance axial T2-weighted A) and FLAIR B) (case 1) image displays diffuse subcortical lesions in right temporal, frontal, parietal, occipital lobes, and left parietal lobes. C) (case 9) image displays multiple subcortical lesions in bilateral hemispheres. D) (case 12) image displays multiple lesions in bilateral basal ganglia, centrum ovale and subcortical regions.

Tables

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    Table 1

    The clinical profiles of patients with HIV infection.

    SymptomsNumber
    Fever4/12
    Weakness9/12
    Memory5/12
    Seizure2/17
    Neroimage abnormal11/12
    PN1/12
    Encephalopathy4/12
    Encephalitis3/12
    MS1/12
    CI2/12
    Other1/12
    • CI - Cerebral infarction, PN - periphral neuropathy, MS - multiple sclerosis

    • View popup
    Table 2

    The laboratory data of patients with HIV infection.

    CasesSerum
    ESR 0-15 (mm/h)TG-Ab, TPO-AbIgG 7.51-15.6IgA 0.82-4.53IgM 0.46-3.04Pressure 80-180 (mmH2O)WBC (×106/l)Protein
    (g/L)
    135-18.06.571.91130547
    244both­21.22.091.30110675
    35-14.21.650.96210355
    422TPO-Ab ­13.63.030.56170031
    56-14.86.741.42130151
    6NANA28.64.372.3221014205
    792-19.77.871.34NA
    820-NANANA3305566
    9NA-24.96.952.6640537
    1018-10.65.50.66150466
    1130-NANA
    1266-NA110--
    CasesCSF
    Glucose 45-80 (mg/dl)Chlorine 118-128 (mmol/L)IgG syntdetic rate <13 (mg/24h)3 major stainCell testOBIgG 0.48-5.86IgA 0.0-0.2IgM 0.0-0.2
    (g/L)
    15111534.0-Lym=90%-201.411.55
    25211412.8-Lym=95%+34.60.110.5
    347121NA-Lym=90%+16.90.650.43
    454111NA---4.460.390.07
    558119NA-Lym=10%, Mo=90%NA15.72.130.66
    661116NA-NANANANANA
    7NA
    842114NAPositive ink stainMNC=33%, PLE=67%6.511.150.48
    93311539.54-+15.32.310.47
    1043118-NA
    11NA
    12-1106.250.56
    • PLE - pleocaryocyte, The 3 major stain: the gram, acid-fast and Indian ink stain, ESR - erythrocyte sedimentation rate, TG-Ab - thyroglobulin antibody, TPO-Ab - thyroid-peroxidase antibody, NA - not available

    • CSF - cerebrospinal fluid, WBC - white blood cell, OB - Oligo-clonal bands, Lym - lymphocyte, Mo - monocyte, MNC - mononuclear cell, PLE - pleocaryocyte, The 3 major stain: the gram, acid-fast and Indian ink stain, NA - not available, + - positive, - - negative

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Neurosciences Journal: 22 (4)
Neurosciences Journal
Vol. 22, Issue 4
1 Oct 2017
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Neurological manifestations, laboratory and neuroimaging features in HIV-infected patients
Hai Chen, Fangju Lin, Shimeng Liu, Yuwei Da, Dongmei Guo
Neurosciences Journal Oct 2017, 22 (4) 311-315; DOI: 10.17712/nsj.2017.4.20160606

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Neurological manifestations, laboratory and neuroimaging features in HIV-infected patients
Hai Chen, Fangju Lin, Shimeng Liu, Yuwei Da, Dongmei Guo
Neurosciences Journal Oct 2017, 22 (4) 311-315; DOI: 10.17712/nsj.2017.4.20160606
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