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Research ArticleOriginal Article
Open Access

Assessment of physicians’ knowledge and attitudes in the management of febrile seizures

Fahad A. Bashiri, Anfal A. Al Shalawi, Muddathir H. Hamad, Hadeel F. Al Saif, Elshazaly Saeed, Amjad F. Al Shehri and Khalid A. Alhasan
Neurosciences Journal October 2018, 23 (4) 314-319; DOI: https://doi.org/10.17712/nsj.2018.4.20180097
Fahad A. Bashiri
From the Department of Pediatrics (Bashiri, Hamad), Division of Pediatric Neurology, Department of Pediatrics (Alshalawi, Alsaif, Alshehri, Alhasan), College of Medicine, King Khalid University Hospital, from Prince Abdullah bin Khaled Celiac Disease Research Chair (Saeed), King Saud University, Riyadh, Kingdom of Saudi Arabia
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Anfal A. Al Shalawi
From the Department of Pediatrics (Bashiri, Hamad), Division of Pediatric Neurology, Department of Pediatrics (Alshalawi, Alsaif, Alshehri, Alhasan), College of Medicine, King Khalid University Hospital, from Prince Abdullah bin Khaled Celiac Disease Research Chair (Saeed), King Saud University, Riyadh, Kingdom of Saudi Arabia
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Muddathir H. Hamad
From the Department of Pediatrics (Bashiri, Hamad), Division of Pediatric Neurology, Department of Pediatrics (Alshalawi, Alsaif, Alshehri, Alhasan), College of Medicine, King Khalid University Hospital, from Prince Abdullah bin Khaled Celiac Disease Research Chair (Saeed), King Saud University, Riyadh, Kingdom of Saudi Arabia
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Hadeel F. Al Saif
From the Department of Pediatrics (Bashiri, Hamad), Division of Pediatric Neurology, Department of Pediatrics (Alshalawi, Alsaif, Alshehri, Alhasan), College of Medicine, King Khalid University Hospital, from Prince Abdullah bin Khaled Celiac Disease Research Chair (Saeed), King Saud University, Riyadh, Kingdom of Saudi Arabia
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Elshazaly Saeed
From the Department of Pediatrics (Bashiri, Hamad), Division of Pediatric Neurology, Department of Pediatrics (Alshalawi, Alsaif, Alshehri, Alhasan), College of Medicine, King Khalid University Hospital, from Prince Abdullah bin Khaled Celiac Disease Research Chair (Saeed), King Saud University, Riyadh, Kingdom of Saudi Arabia
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Amjad F. Al Shehri
From the Department of Pediatrics (Bashiri, Hamad), Division of Pediatric Neurology, Department of Pediatrics (Alshalawi, Alsaif, Alshehri, Alhasan), College of Medicine, King Khalid University Hospital, from Prince Abdullah bin Khaled Celiac Disease Research Chair (Saeed), King Saud University, Riyadh, Kingdom of Saudi Arabia
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Khalid A. Alhasan
From the Department of Pediatrics (Bashiri, Hamad), Division of Pediatric Neurology, Department of Pediatrics (Alshalawi, Alsaif, Alshehri, Alhasan), College of Medicine, King Khalid University Hospital, from Prince Abdullah bin Khaled Celiac Disease Research Chair (Saeed), King Saud University, Riyadh, Kingdom of Saudi Arabia
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Article Figures & Data

Tables

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    Table 1

    Distribution of characteristics of study subjects (N=300).

    Characteristicsn (%)
    Gender
     Male178 (59.3)
     Female122 (40.7)
    Age in years
     25-3065 (21.7)
     31-40130 (43.3)
     41-5072 (24.0)
     51-6026 (8.7)
     >607 (2.3)
    Nationality
     Saudi199 (66.3)
     Non-Saudi101 (33.7)
    Current position
     Consultant119 (39.7)
     Specialist92 (30.7)
     Resident89 (29.7)
    Specialty
     General Pediatrics134 (44.7)
     Pediatric Neurology63 (21.0)
     Family Medicine39 (13.0)
     Emergency Physicians64 (21.3)
    Years in practice
     <5127 (42.3)
     5-1085 (28.3)
     10-1553 (17.7)
     15-2035 (11.7)
    Place of work
     Government hospital269 (89.7)
     Private hospital31 (10.3)
    Level of care
     Primary care30 (10.0)
     Secondary care72 (24.0)
     Tertiary care198 (66.0)
    Aware of guidelines for management of Febrile Seizure
     Yes206 (68.7)
     No94 (31.3)
    • View popup
    Table 2

    Comparison of correct answers towards knowledge of guidelines for management of febrile seizure in relation to the position of study subjects.

    ItemsCorrect answerP-value
    Resident (n=89)Specialist (n=92)Consultant (n=119)
    n (%)
    K1- Febrile seizure is accompanied by fever without intracranial infection, metabolic disturbance, or history of afebrile seizure.75(84.3)79(85.9)103(86.6)0.895
    K2- In febrile seizure, the temperature is 38°C or above64(71.9)66(71.7)90(75.6)0.766
    K3- Febrile seizure occurs at 6-60 months of age.75(84.3)76(82.6)106(89.1)0.374
    K4- Febrile seizure is the most common convulsive event in children younger than 60 months of age.65(73.0)72(78.3)105(88.2)ǂ0.018*
    K5- There are 2 types of febrile seizure: simple and complex.68(76.4)74(80.4)105(88.2)ǂ0.032*
    K6- Simple febrile seizure is a generalized seizure, lasts for less than 15 min, and does not recur within 24 hours.69(77.5)79(85.9)106(89.1)ǂ0.044*
    K7- Complex febrile seizure is a focal seizure, lasts more than 15 min, and recurs within 24 hours.70(78.7)73(79.3)100(84.0)0.551
    K8- Children who had a simple febrile seizure had no evidence of increased mortality or mental retardation.74(83.1)72(78.3)106(89.1)0.101
    • ↵* Statistically significant - p<0.05 (by χ2-test), ǂK4 - Significantly higher than Resident & Specialist; K5 - Significantly higher than Resident & Specialist; K6 - Significantly higher than Resident, but not different from Specialist (by residual analysis)

    • View popup
    Table 3

    Comparison of correct answers towards knowledge of guidelines for management of febrile seizure between the study subjects of general pediatrics and pediatric neurology specialties.

    ItemsGeneral pediatrics (n=134)Pediatric neurology (n=63)P-value*
    n(%)n(%)
    K1- Febrile seizure is accompanied by fever without intracranial infection, metabolic disturbance, or history of afebrile seizure.115 (85.8)55(87.3)0.778
    K2- In febrile seizure, the temperature is 38 °C or above.103 (76.9)42(66.7)0.130
    K3- Febrile seizure occurs at 6-60 months of age.110(82.1)57(90.5)0.127
    K4- Febrile seizure is the most common convulsive event in children younger than 60 months of age.99(73.9)53(84.1)0.110
    K5- There are 2 types of febrile seizure: simple and complex.109(81.3)54(85.7)0.449
    K6- Simple febrile seizure is a generalized seizure, last for less than 15 min, and does not recure within 24 hours.112(83.6)56(88.9)0.327
    K7- Complex febrile seizure is a focal seizure, lasts more than 15 min, and recure within 24 hours.105(78.4)56(88.9)0.074
    K8- Children who had a simple febrile seizure had no evidence of increased mortality or mental retardation.115(85.8)52(82.5)0.550
    • View popup
    Table 4

    Comparison of mean scores of attitude towards the management of febrile seizure in relation to the professional category of responders.

    ItemsMean±SD scoreP-value
    ResidentSpecialistConsultant
    A1- Lumbar puncture should be performed in any infant younger than 12 months, who presents with a seizure and fever, without meningeal signs.3.54±1.482.90±1.57ǂ3.47±1.540.008*
    A2- Lumbar puncture is an option in the child who presents with a seizure and fever and was pre-treated with antibiotics.3.10±1.273.36±1.513.28±1.400.449
    A3- EEG should not be performed in the evaluation of a neurologically healthy child with a simple febrile seizure.3.93±1.283.98±1.474.19±1.320.325
    A4- EEG should not be performed in the evaluation of a neurologically healthy child with a complex febrile seizure.2.51±1.222.64±1.392.64±1.300.720
    A5- Electrolytes (calcium, phosphorus, magnesium, blood glucose) and complete cell count should not be performed routinely for the sole purpose of identifying the cause of febrile seizure.2.46±1.43ǂ3.09±1.633.07±1.590.008*
    A6- Neuroimaging should not be performed in the routine evaluation of the child with simple febrile seizure.4.00±1.18ǂ4.27±1.314.46±1.050.021*
    A7- Neuroimaging should not be performed in the routine evaluation of the child with complex febrile seizure.2.45±1.182.59±1.392.79±1.320.167
    A8- Continuous use of phenobarbital is recommended for the treatment of febrile seizure.1.65±0.971.67±1.191.59±1.170.844
    A9- Continuous use of levetiracetam is recommended for the treatment of febrile seizure.1.56±0.851.75±1.201.63±1.060.474
    A10- Continuous use of valproic acid is recommended for the treatment of febrile seizure.1.60±0.871.66±1.161.52(0.950.591
    A11- Intermittent use of oral diazepam during febrile illness is recommended for the treatment of febrile seizure.2.77±1.432.78±1.612.71±1.540.921
    A12- Continuous use of antiepileptic drugs is recommended for the treatment of complex febrile seizure.2.40±1.232.48±1.352.34±1.270.728
    A13- If seizure is prolonged more than 5 min, the treatment is rectal diazepam or buccal midazolam.4.05±1.084.13±1.284.17±1.140.789
    A14- Regular use of antipyretic drugs will prevent febrile seizure.3.00±1.392.53±1.432.60±1.540.065
    • ↵* Statistically significant - p<0.05 (by One-way Anova)ǂ, A1 - Significantly lower than Resident & Consultant; A5 - Significantly lower than Specialists & Consultant; A6 - Significantly lower than Consultant but not different with specialist (by Tukey’s test).

    • View popup
    Table 5

    Comparison of mean scores of attitude towards the management of febrile seizure in relation to the specialties of study subjects.

    ItemsGeneral pediatricPediatric neurologyFamily medicineEmergencyP-value
    Mean±SD score
    A1- Lumbar puncture should be performed in any infant younger than 12 months, who presents with a seizure and fever, without meningeal signs.3.53±1.453.90±1.393.21±1.592.36±1.48ǂ<0.001*
    A2- Lumbar puncture is an option in the child who presents with a seizure and fever and was pre-treated with antibiotics.3.13±1.403.44±1.433.10±1.293.39±1.430.362
    A3- EEG should not be performed in the evaluation of a neurologically healthy child with a simple febrile seizure4.01±1.334.40±1.203.67±1.474.03±1.440.060
    A4- EEG should not be performed in the evaluation of a neurologically healthy child with a complex febrile seizure.2.48±1.222.83±1.392.54±1.452.67±1.310.344
    A5- Electrolytes (calcium, phosphorus, magnesium, blood glucose) and complete cell count should not be performed routinely for the sole purpose of identifying the cause of febrile seizure.2.57±1.523.10±1.602.38±1.41ǂ3.67±1.48<0.001*
    A6- Neuroimaging should not be performed in the routine evaluation of the child with simple febrile seizure.4.22±1.154.52±1.083.64±1.40ǂ4.48±1.110.001*
    A7- Neuroimaging should not be performed in the routine evaluation of the child with complex febrile seizure.2.38±1.12ǂ3.02±1.412.31±1.42ǂ2.95±1.360.001*
    A8- Continuous use of phenobarbital is recommended for the treatment of febrile seizure.1.62±1.031.43±1.031.92±1.091.69±1.340.177
    A9- Continuous use of levetiracetam is recommended for the treatment of febrile seizure.1.63±0.951.48±1.01.90±0.991.69±1.300.263
    A10- Continuous use of valproic acid is recommended for the treatment of febrile seizure.1.54±0.891.41±0.931.87±1.031.67±1.220.122
    A11- Intermittent use of oral diazepam during febrile illness is recommended for the treatment of febrile seizure.2.87±1.512.87±1.622.97±1.422.25±1.48ǂ0.031*
    A12- Continuous use of antiepileptic drugs is recommended for the treatment of complex febrile seizure.2.60±1.271.92±1.18ǂ2.54±1.272.36±1.310.005*
    A13- If seizure is prolonged more than 5 min, the treatment is rectal diazepam or buccal midazolam.4.15±1.114.37±1.113.74±1.094.06±1.320.067
    A14- Regular use of antipyretic drugs will prevent febrile seizure.2.90±1.452.24±1.41ǂ2.92±1.402.58±1.540.017*
    • ↵* Statistically significant p<0.05 (By One way Anova), ǂA1- Significantly lower than other 3 specialties, A5- Significantly lower than other 3 specialties, A6- Significantly lower than other 3 specialties, A7- Significantly lower than other 2 specialties, A11- Significantly lower than other 3 specialties, A12- Significantly lower than other 3 specialties, A14- Significantly lower than other 3 specialties (by Tukey’s test). EEG - Electroencephalogram, LP - Lumbar puncture

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Assessment of physicians’ knowledge and attitudes in the management of febrile seizures
Fahad A. Bashiri, Anfal A. Al Shalawi, Muddathir H. Hamad, Hadeel F. Al Saif, Elshazaly Saeed, Amjad F. Al Shehri, Khalid A. Alhasan
Neurosciences Journal Oct 2018, 23 (4) 314-319; DOI: 10.17712/nsj.2018.4.20180097

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Assessment of physicians’ knowledge and attitudes in the management of febrile seizures
Fahad A. Bashiri, Anfal A. Al Shalawi, Muddathir H. Hamad, Hadeel F. Al Saif, Elshazaly Saeed, Amjad F. Al Shehri, Khalid A. Alhasan
Neurosciences Journal Oct 2018, 23 (4) 314-319; DOI: 10.17712/nsj.2018.4.20180097
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