Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • Saudi Medical Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Neurosciences Journal
  • Other Publications
    • Saudi Medical Journal
  • My alerts
  • Log in
Neurosciences Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

Prevalence of epilepsy in Saudi pregnant women and possible effects of anti-epileptic drugs on pregnancy outcomes

Mona H. AlSheikh
Neurosciences Journal January 2020, 25 (1) 32-37; DOI: https://doi.org/10.17712/nsj.2020.1.20190077
Mona H. AlSheikh
From the Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

Article Figures & Data

Tables

    • View popup
    Table 1

    Demographic and clinical characteristics of epileptic patients.

    VariablesMonotherapy
    39 (57.3)
    Polytherapy
    21 (30.9)
    Without medication
    8 (11.8)
    P-value
    n (%)
    Average age ±SD (min-max)28.79±5.831.2±6.323.6±2.10.12
    (17–32)(18–35)(21–26)
    Age of seizure onset17.8±9.115.7±6.114.1±8.10.6
    (1–35)(3–32)(2–29)
    Disease duration (years)12.6±8.97.3±5.69.2±9.10.7
    (1–35)(3–32)(2–29)
    Duration of use of AED (years)11.7±9.0712.3±7.31.8±2.020.1
    (0.17–31)(0.08–24)(0–4)
    Seizure semiology, n (%)
    Focal seizure16 (41.0)11 (52.4)3 (37.5)0.36
    Generalized seizure23 (59.0)10 (47.6)5 (62.5)
    Number of pregnancies, n (%)
    Nulliparous27 (69.2)14 (66.7)6 (75.0)0.34
    Multiparous12 (30.8)7 (33.3)2 (25.0)
    Electroencephalogram, n (%)
    Normal15 (38.5)5 (23.8)5 (62.5)0.6
    Abnormal24 (61.5)16 (76.2)3 (37.5)
    Cerebral imaging (MRI), n (%)
    Abnormal7 (17.9)6 (28.6)0 (0)0.5
    • View popup
    Table 2

    Association between the frequency of seizures during pregnancy with neonatal birth weight, head circumference and height.

    ParametersSeizure frequency in pregnancy: unchanged / decreased / increasedP-value
    UnchangedDecreasedIncreased
    Mean±SDMedian (Min-Max)
    Birth weight (g)3064±6233105 (1360–4210)3324±6673410 (1200–4150)3122±6753110 (1910–3620)0.812
    Head circumference (cm)33.127±2.46934 (28–37)34.965±1.99034 (30–38)32.767±2.36933 (29–37)0.832
    Height (cm)48.47±3.44150 (40–53)49.08±3.77749 (41–51)47.75±3.30649 (40–52)0.626
    • View popup
    Table 3

    Clinical data of patients experiencing fetal/neonatal malformation or stillbirth.

    Sr #Seizure SemiologyMedication usedFrequency of seizures during pregnancyMalformation CategoryMalformation Name
    Patient 1Generalized seizureCBZ 900 mg/dayIncreasedIntrauterine deathSevere intrauterine growth restriction leading to intrauterine fetal death
    Patient 2Focal seizureCBZ 1000 mg/dayLMT 200 mg/dayDecreasedFacial malformationCleft lip and cleft palate
    Patient 3Generalized seizureVPA 500 mg/dayLMT 50 mg/dayUnchangedIntrauterine deathFetal anencephaly leading to still birth
    Patient 4Focal seizureCBZ 400 mg/dayUnchangedOrgan malformationTetralogy of Fallot
    Patient 5Generalized seizureVPA 1250 mg/dayLMT 800 mg/dayUnchangedOrgan malformationAtrial septal defect
    Patient 6Generalized seizureNo drug useUnchangedFacial + Organ malformationFetal gastroschisis along with cleft palate
    CBZ - carbamazepine, VPA - valproic acid, LMT - lamotrigine
PreviousNext
Back to top

In this issue

Neurosciences Journal: 25 (1)
Neurosciences Journal
Vol. 25, Issue 1
1 Jan 2020
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Neurosciences Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Prevalence of epilepsy in Saudi pregnant women and possible effects of anti-epileptic drugs on pregnancy outcomes
(Your Name) has sent you a message from Neurosciences Journal
(Your Name) thought you would like to see the Neurosciences Journal web site.
Citation Tools
Prevalence of epilepsy in Saudi pregnant women and possible effects of anti-epileptic drugs on pregnancy outcomes
Mona H. AlSheikh
Neurosciences Journal Jan 2020, 25 (1) 32-37; DOI: 10.17712/nsj.2020.1.20190077

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Prevalence of epilepsy in Saudi pregnant women and possible effects of anti-epileptic drugs on pregnancy outcomes
Mona H. AlSheikh
Neurosciences Journal Jan 2020, 25 (1) 32-37; DOI: 10.17712/nsj.2020.1.20190077
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Acknowledgment
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Ranking the difficulty of the cognitive tasks in Dual-Tasks during walking in healthy adults
  • Exploring physiotherapist’s ability to identify cauda equina syndrome early
  • Does the severity of facet joint osteoarthritis affect facet medial branch radiofrequency thermocoagulation results?
Show more Original Article

Similar Articles

Navigate

  • home

More Information

  • Help

Additional journals

  • All Topics

Other Services

  • About

© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

Powered by HighWire