Clinical outcomes of optic neuritis: A retrospective study at a tertiary medical center in Saudi Arabia

Article Figures & Data

Table 1

- Demographics of the optic neuritis patients, Saudi Arabia.

Personal data	No	(%)
Age in years
10-20	2	(13.3)
20-30	3	(20.0)
30-40	6	4(0.0)
> 40	4	(26.7)
Gender
Male	2	(13.3)
Female	13	(86.7)
Nationality
Non-Saudi	1	(6.7)
Saudi Arabian	14	(93.3)
Smoking
Ex-Smoker	1	(6.7)
No	14	(93.3)
Do you have a history of chronic diseases :
No	1	(6.7)
Yes	14	(93.3)

Table 2

- Clinical data of optic neuritis among study patients in Saudi Arabia

ON clinical data	No	(%)
Cause of the disease
Multiple Sclerosis	11	(73.3)
Neuromyelitis optica spectrum disorders (NMOSD)	4	(26.7)
Disease duration
>25 days	13	(86.7)
11-15 days	2	(13.3)
Affected side
Right	2	(13.3)
Left	4	(26.7)
Bilateral	9	(60.0)
Number of attacks
One attack of optic neuritis	6	(40.0)
Two or more attacks of optic neuritis	9	(60.0)

Table 3

- Clinical signs and symptoms of optic neuritis among study patients, Saudi Arabia.

Table 4

- Clinical outcome of optic neuritis among study patients, Saudi Arabia.

Outcome	No	(%)
Vision outcome in optic neuritis patients
<20/200, loss of field of vision	1	(6.7)
20/200	7	(46.7)
Improved better than 20/200	5	(33.3)
loss of field of vision	2	(13.3)
Vision prognosis for optic neuritis
Complete resolution of their symptoms with some residual vision loss	1	(6.7)
Complete resolution of their symptoms without some residual vision loss	4	(26.7)
Continued visual change	4	(26.7)
Reduced color vision	3	(20.0)
Missing	3	(20.0)
Treatment
Immunomodulating drugs	8	(53.3)
IV steroid	3	(20.0)
Oral steroid	4	(26.7)

Table 5

- Distribution of patients’ optic neuritis clinical data by their age, Kingdom of Saudi Arabia.

Clinical data	Age in years				P-value
	< 30 years		> 30 years
	No	(%)	No	(%)
Pupillary reaction
Defective	3	(60.0)	4	40.0)	.464^{^$}
Normal	2	(40.0)	6	60.0)	.464^{^$}
Painful eye movement
Absent	3	(60.0)	7	70.0)	.699^{^$}
Present	2	(40.0)	3	30.0)	.699^{^$}
Color vision
Decreased	3	(60.0)	6	(60.0)	1.0
Normal	2	(40.0)	4	(40.0)	1.0
Visual Acuity
<20/200	0	(0.0)	1	(10.0)	.651^{^$}
>20/200	3	(60.0)	4	(40.0)
20/200	2	(40.0)	5	(50.0)
Optic disc
Blurred	2	(40.0)	3	(30.0)	.509
Normal	2	(40.0)	2	(20.0)
Pale	1	(20.0)	5	(50.0)
Brain MRI findings
Multiple lesions	2	(40.0)	4	(40.0)	.325^{^$}
Normal	3	(60.0)	3	(30.0)
Not done	0	(0.0)	3	(30.0)
Number of attacks
One attack of optic neuritis	1	(20.0)	5	(50.0)	.264
Two or more attacks of optic neuritis	4	(80.0)	5	(50.0)	.264
Vision consequences in optic neuritis patients
<20/200, Presence of loss of field of vision	0	(0.0)	1	(10.0)	.596^{^$}
20/200	3	(60.0)	4	(40.0)
Improved better than 20/200	2	(40.0)	3	(30.0)
Presence of loss of field of vision	0	(0.0)	2	(20.0)
Vision prognosis for optic neuritis (3 missing cases)
Complete resolution of their symptoms with some residual vision loss	0	(0.0)	1	(10.0)	.558^{^$}
Complete resolution of their symptoms without some residual vision loss	2	(40.0)	2	(20.0)
Continued visual change	2	(40.0)	2	(20.0)
Reduced color visio	0	(0.0)	3	(30.0)
Missing	1	(20.0)	2	(20.0)

P: Pearson X² test,

Table 6

- Distribution of patients’ optic neuritis clinical data by their disease duration, Saudi Arabia.

Clinical data	Disease duration				P-value
	>25 days		11-15 days
	No	(%)	No	(%)
Pupillary reaction
Defective	6	(46.2)	1	(50.0)	.919
Normal	7	(53.8)	1	(50.0)	.919
Painful eye movement
Absent	10	(76.9)	0	(0.0)	.032^*
Present	3	(23.1)	2	(100.0)	.032^*
Color vision
Decreased	8	(61.5)	1	(50.0)	.756
Normal	5	(38.5)	1	(50.0)	.756
Visual Acuity
<20/200	1	(7.7)	0	(0.0)	.921
>20/200	6	(46.2)	1	(50.0)
20/200	6	(46.2)	1	(50.0)
Optic disc
Blurred	5	(38.5)	0	(0.0)	.177
Normal	4	(30.8)	0	(0.0)
Pale	4	(30.8)	2	(100.0)
Brain MRI findings
Multiple lesions	5	(38.5)	1	(50.0)	.364
Normal	6	(46.2)	0	(0.0)
Not done	2	(15.4)	1	(50.0)
Number of attacks
One attack of optic neuritis	5	(38.5)	1	(50.0)	.756
Two or more attacks of optic neuritis	8	(61.5)	1	(50.0)	.756
Vision consequences in optic neuritis patients
<20/200, Presence loss of field of vision	1	(7.7)	0	(0.0)	.883
20/200	6	(46.2)	1	(50.0)
Improved better than 20/200	4	(30.8)	1	(50.0)
Presence of loss of field of vision	2	(15.4)	0	(0.0)
Vision prognosis for optic neuritis
Complete resolution of their symptoms with some residual vision loss	1	(7.7)	0	(0.0)	.049^*
Complete resolution of their symptoms without some residual vision loss	4	(30.8)	0	(0.0)
Continued visual change	4	(30.8)	0	(0.0)
Reduced color vision	3	(23.1)	0	(0.0)
Missing	1	(7.7)	2	(100)