Brief ReportClinical Practice Guidelines
Open Access
Saudi clinical practice guidelines for the treatment and prevention of migraine headache
Faisal A. Al-Suwaidan, Hajer Y. Almudaiheem, Haifa F. Alotaibi, Waleed A. Alhazzani, Khalid W. Al-Quliti, Khalidah A. Alenzi, Bedor A. Al-Omari, Majed M. Alabdali, Abubker W. Omaer, Saleh M. Alrajhi, Ali N. Alshoaiby and Ahmed H. Al-Jedai
Neurosciences Journal April 2025, 30 (2) 77-91; DOI: https://doi.org/10.17712/nsj.2025.2.20240097
Faisal A. Al-Suwaidan
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
MBBS, MScHajer Y. Almudaiheem
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
Pharm. D, MScHaifa F. Alotaibi
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
MD, MPHWaleed A. Alhazzani
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
MD, MScKhalid W. Al-Quliti
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
MBBS, MDKhalidah A. Alenzi
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
EMBA, RPHBedor A. Al-Omari
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
B.Sc. Pharm, SSCIMPMajed M. Alabdali
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
MD, MScAbubker W. Omaer
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
PharmDSaleh M. Alrajhi
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
DO, EMHAAli N. Alshoaiby
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
MD, MScAhmed H. Al-Jedai
from the Division of Neurology (Al-Suwaidan), Department of Medicine, Security Forces Hospital, Neurology Clinical Lead (Al-Suwaidan), Ministry of Health, from the College of Medicine (Al-Suwaidan), Princess Nourah Bint Abdulrahman University, from the College of Medicine (Al-Suwaidan), Dar Al-Uloom University, from Scientific Research Centre (Alotaibi, Alhazzani), Ministry of Defence Health Services, from the Department of Pharmaceutical Care Services (Al-Omari), Prince Sultan Military Medical City, from King Saud Medical City (Omaer), from Department of Family Medicine (Alrajhi), Administration of Anesthesiology & Perioperative Medicine (Alshoaiby), King Fahad Medical City, from the Colleges of Medicine and Pharmacy (Al-Jedai), Alfaisal University, from the Solid Organ Transplant (Al-Jedai), King Faisal Specialist Hospital & Research Centre, from The Saudi Society of Clinical Pharmacy (Al-Jedai, Almudaiheem), Riyadh, Saudi Arabia, and from the Department of Medicine (Al-Quliti), College of Medicine, Taibah University, National Guard Hospital, Madinah, and from Executive Management of Transformation, Planning, and Business Development (Alenzi), Tabuk Health Cluster, Tabuk, and from the Department of Neurology (Alabdali), College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
Pharm.D., MBA
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In this issue
Saudi clinical practice guidelines for the treatment and prevention of migraine headache
Faisal A. Al-Suwaidan, Hajer Y. Almudaiheem, Haifa F. Alotaibi, Waleed A. Alhazzani, Khalid W. Al-Quliti, Khalidah A. Alenzi, Bedor A. Al-Omari, Majed M. Alabdali, Abubker W. Omaer, Saleh M. Alrajhi, Ali N. Alshoaiby, Ahmed H. Al-Jedai
Neurosciences Journal Apr 2025, 30 (2) 77-91; DOI: 10.17712/nsj.2025.2.20240097
Saudi clinical practice guidelines for the treatment and prevention of migraine headache
Faisal A. Al-Suwaidan, Hajer Y. Almudaiheem, Haifa F. Alotaibi, Waleed A. Alhazzani, Khalid W. Al-Quliti, Khalidah A. Alenzi, Bedor A. Al-Omari, Majed M. Alabdali, Abubker W. Omaer, Saleh M. Alrajhi, Ali N. Alshoaiby, Ahmed H. Al-Jedai
Neurosciences Journal Apr 2025, 30 (2) 77-91; DOI: 10.17712/nsj.2025.2.20240097
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