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Case ReportCASE REPORTS
Open Access

Transient opsoclonus-myoclonus syndrome secondary to neuroblastoma

Roshan Koul, Amna Al-Futaisi, Ranjan Williams, Hashim Javad and Alexander Chacko
Neurosciences Journal July 2007, 12 (3) 253-255;
Roshan Koul
Department of Child Health, Sultan Qaboos University Hospital, BW-1, PO Box 38, Al-Khod 123, Oman. E-mail: [email protected] / [email protected]
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Amna Al-Futaisi
Department of Child Health, Sultan Qaboos University Hospital, BW-1, PO Box 38, Al-Khod 123, Oman. E-mail: [email protected] / [email protected]
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Ranjan Williams
Department of Child Health, Sultan Qaboos University Hospital, BW-1, PO Box 38, Al-Khod 123, Oman. E-mail: [email protected] / [email protected]
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Hashim Javad
Department of Child Health, Sultan Qaboos University Hospital, BW-1, PO Box 38, Al-Khod 123, Oman. E-mail: [email protected] / [email protected]
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Alexander Chacko
Department of Child Health, Sultan Qaboos University Hospital, BW-1, PO Box 38, Al-Khod 123, Oman. E-mail: [email protected] / [email protected]
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Abstract

We report a 2.5-year-old girl who presented with acute history of fluctuating level of consciousness in the form of drowsiness, extreme irritability, and involuntary abnormal movements in the form of shaking of the whole body. She was treated with acyclovir empirically, contemplating herpes simplex virus encephalitis. Overtime she improved substantially. The opsoclonus, myoclonus, and ataxia disappeared without treatment. However, 6 weeks later she presented again with classic opsoclonus-myoclonus syndrome. The investigations revealed neuroblastoma. This case illustrates that transient opsoclonus-myoclonus may occur with neuroblastoma and should not be assumed to be due to viral cause. Thus, a thorough search for occult neuroblastoma should be initiated even if opsoclonus-myoclonus resolves spontaneously.

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Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Neurosciences Journal: 12 (3)
Neurosciences Journal
Vol. 12, Issue 3
1 Jul 2007
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Transient opsoclonus-myoclonus syndrome secondary to neuroblastoma
Roshan Koul, Amna Al-Futaisi, Ranjan Williams, Hashim Javad, Alexander Chacko
Neurosciences Journal Jul 2007, 12 (3) 253-255;

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Transient opsoclonus-myoclonus syndrome secondary to neuroblastoma
Roshan Koul, Amna Al-Futaisi, Ranjan Williams, Hashim Javad, Alexander Chacko
Neurosciences Journal Jul 2007, 12 (3) 253-255;
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© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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