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Research ArticleOriginal Article
Open Access

Efficacy and safety of levetiracetam in the management of seizures in neonates

Mostafa Sedighi, Farzaneh Asadi, Nasrin Moradian, Mazyar Vakiliamini and Mohamad Moradian
Neurosciences Journal July 2016, 21 (3) 232-235; DOI: https://doi.org/10.17712/nsj.2016.3.20150726
Mostafa Sedighi
From the Department of Neurology (Sedighi, Asadi), the Department of Neonatology (Vakiliamini), Mohamad Kermanshahi Hospital, the Department of Neurology (Moradian N, Moradian M), Imam Reza Hospital, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Islamic Republic of Iran
MD
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Farzaneh Asadi
From the Department of Neurology (Sedighi, Asadi), the Department of Neonatology (Vakiliamini), Mohamad Kermanshahi Hospital, the Department of Neurology (Moradian N, Moradian M), Imam Reza Hospital, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Islamic Republic of Iran
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Nasrin Moradian
From the Department of Neurology (Sedighi, Asadi), the Department of Neonatology (Vakiliamini), Mohamad Kermanshahi Hospital, the Department of Neurology (Moradian N, Moradian M), Imam Reza Hospital, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Islamic Republic of Iran
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  • For correspondence: [email protected]
Mazyar Vakiliamini
From the Department of Neurology (Sedighi, Asadi), the Department of Neonatology (Vakiliamini), Mohamad Kermanshahi Hospital, the Department of Neurology (Moradian N, Moradian M), Imam Reza Hospital, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Islamic Republic of Iran
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Mohamad Moradian
From the Department of Neurology (Sedighi, Asadi), the Department of Neonatology (Vakiliamini), Mohamad Kermanshahi Hospital, the Department of Neurology (Moradian N, Moradian M), Imam Reza Hospital, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Islamic Republic of Iran
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    Figure 1

    Consort flowchart of patient enrollment and disposition.

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    Table 1

    Demographic and clinical characteristics of 50 newborns clinically diagnosed with seizures in Iran.

    Gendern(%)
     Male29(58)
     Female21(42)
    Gestational age
     ≤36 weeks+6 days24(48)
     ≥3726(52)
    Seizure etiology
     Unknown34(68)
     Meningitis7(14)
     Hypoxic ischemic encephalopathy3(6)
     Inborn error metabolic disorder3(6)
     Withdrawal syndrome1(2)
     Kernicterus2(4)
    Seizure subtype
     Subtle10(20)
     Tonic23(46)
     Clonic10(20)
     Myoclonic5(10)
     Spasm2(4)
    Intracranial sonography
     Normal36(72)
     Intracranial hemorrhage8(16)
     Hydrocephaly3(6)
     Brain cyst2(4)
     Intracranial hemorrhage and hydrocephaly1(2)
    First EEG
     Normal38(76)
     Abnormal12(24)
    Follow up EEG
     Normal48(96)
     Abnormal2(2)
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Neurosciences Journal: 21 (3)
Neurosciences Journal
Vol. 21, Issue 3
1 Jul 2016
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Efficacy and safety of levetiracetam in the management of seizures in neonates
Mostafa Sedighi, Farzaneh Asadi, Nasrin Moradian, Mazyar Vakiliamini, Mohamad Moradian
Neurosciences Journal Jul 2016, 21 (3) 232-235; DOI: 10.17712/nsj.2016.3.20150726

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Efficacy and safety of levetiracetam in the management of seizures in neonates
Mostafa Sedighi, Farzaneh Asadi, Nasrin Moradian, Mazyar Vakiliamini, Mohamad Moradian
Neurosciences Journal Jul 2016, 21 (3) 232-235; DOI: 10.17712/nsj.2016.3.20150726
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