Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • Saudi Medical Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Neurosciences Journal
  • Other Publications
    • Saudi Medical Journal
  • My alerts
  • Log in
Neurosciences Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

Protective role of astragalus injection in spinal cord ischemia-reperfusion injury in rats

Liya Zhou, Zhenfei Song, Liwen Zhou, Yongchi Qiu, Nan Hu, Yong Hu and Xingming Hu
Neurosciences Journal April 2018, 23 (2) 116-121; DOI: https://doi.org/10.17712/nsj.2018.4.20170391
Liya Zhou
From the Department of Orthopedics (Zhou Li-ya, Song, Qiu, Hu N, Hu Y, Hu X), Xiangyang Hospital of Traditional Chinese Medicine, Department of Anesthesiology (Zhou Li-wen), Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Zhenfei Song
From the Department of Orthopedics (Zhou Li-ya, Song, Qiu, Hu N, Hu Y, Hu X), Xiangyang Hospital of Traditional Chinese Medicine, Department of Anesthesiology (Zhou Li-wen), Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China
MB
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Liwen Zhou
From the Department of Orthopedics (Zhou Li-ya, Song, Qiu, Hu N, Hu Y, Hu X), Xiangyang Hospital of Traditional Chinese Medicine, Department of Anesthesiology (Zhou Li-wen), Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Yongchi Qiu
From the Department of Orthopedics (Zhou Li-ya, Song, Qiu, Hu N, Hu Y, Hu X), Xiangyang Hospital of Traditional Chinese Medicine, Department of Anesthesiology (Zhou Li-wen), Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China
MS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nan Hu
From the Department of Orthopedics (Zhou Li-ya, Song, Qiu, Hu N, Hu Y, Hu X), Xiangyang Hospital of Traditional Chinese Medicine, Department of Anesthesiology (Zhou Li-wen), Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China
MS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yong Hu
From the Department of Orthopedics (Zhou Li-ya, Song, Qiu, Hu N, Hu Y, Hu X), Xiangyang Hospital of Traditional Chinese Medicine, Department of Anesthesiology (Zhou Li-wen), Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China
MB
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xingming Hu
From the Department of Orthopedics (Zhou Li-ya, Song, Qiu, Hu N, Hu Y, Hu X), Xiangyang Hospital of Traditional Chinese Medicine, Department of Anesthesiology (Zhou Li-wen), Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China
MB
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Figure 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1

    HE staining of rats spinal cord A) Representative HE staining of control spinal cord tissue. Representative HE staining of spinal cord tissue from the ischemic group when ischemia was induced for 32 min, followed by a B) 12-h, C) 24-h, or D) 48-h reperfusion period. Representative HE staining of spinal cord tissue from the Astragalus-treated group. Astragalus injection was administered 30 min before ischemia induction (32 min) followed by a E) 12-h, F) 24-h, or a G) 48-h reperfusion period. All images are shown at 400× magnification.

  • Figure 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2

    Serum neuron-specific enolase (NSE) concentrations among the different groups.

  • Figure 3
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 3

    Aquaporin-4 (AQP-4) protein levels among the different groups.

Tables

  • Figures
    • View popup
    Table 1

    Serum neuron-specific enolase (NSE) concentrations (ng/mL)

    Groups8 h12 h24 h48 h
    Control group2.552.021.81
    I/R group9.98±0.6311.95±0.3410.40±0.778.17±0.78
    Ast group5.28±0.35*6.53±0.57*8.49±0.46*6.29±0.99*
    • ↵* The differences among rats in the I/R group, Ast group, and control group are significant (F=22.329, p<0.01). Furthermore, the NSE levels were significantly higher in the I/R group, compared with the Ast group, at each time point (F=38.646, p<0.01), h - hours, I/R - ischemia-reperfusion

    • View popup
    Table 2

    Aquaporin-4 (AQP-4) gray-scale values.

    Groups8 h12 h24 h48 h
    Control group0.2440.0660.06
    I/R group0.427±0.2340.499±0.2550.554±0.2680.659±0.290
    Ast group0.295±0.119*0.257±0.130*0.231±0.117*0.215±0.096
    • The differences among rats in the I/R group, Ast group, and control group are significant (F=10.482, p<0.01). *At 8 h, 12 h, and 24 h, the difference in the AQP4 level was significant between the I/R group and Ast group (t8h=2.86, t12h=3.611, t24h=4.72, p<0.05). However, the AQP4 level was not significantly different between the I/R and Ast group at 48 h (t=2.513, p>0.05), h - hours, I/R - ischemia-reperfusion

PreviousNext
Back to top

In this issue

Neurosciences Journal: 23 (2)
Neurosciences Journal
Vol. 23, Issue 2
1 Apr 2018
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Neurosciences Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Protective role of astragalus injection in spinal cord ischemia-reperfusion injury in rats
(Your Name) has sent you a message from Neurosciences Journal
(Your Name) thought you would like to see the Neurosciences Journal web site.
Citation Tools
Protective role of astragalus injection in spinal cord ischemia-reperfusion injury in rats
Liya Zhou, Zhenfei Song, Liwen Zhou, Yongchi Qiu, Nan Hu, Yong Hu, Xingming Hu
Neurosciences Journal Apr 2018, 23 (2) 116-121; DOI: 10.17712/nsj.2018.4.20170391

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Protective role of astragalus injection in spinal cord ischemia-reperfusion injury in rats
Liya Zhou, Zhenfei Song, Liwen Zhou, Yongchi Qiu, Nan Hu, Yong Hu, Xingming Hu
Neurosciences Journal Apr 2018, 23 (2) 116-121; DOI: 10.17712/nsj.2018.4.20170391
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Ranking the difficulty of the cognitive tasks in Dual-Tasks during walking in healthy adults
  • Exploring physiotherapist’s ability to identify cauda equina syndrome early
  • Does the severity of facet joint osteoarthritis affect facet medial branch radiofrequency thermocoagulation results?
Show more Original Article

Similar Articles

Navigate

  • home

More Information

  • Help

Additional journals

  • All Topics

Other Services

  • About

© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

Powered by HighWire