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Research ArticleOriginal Article
Open Access

Tolerability and discontinuation rates in teriflunomide-treated patients

A real-world clinical experience

Hind A. Alnajashi, Foziah J. Alshamrani and Mark S. Freedman
Neurosciences Journal July 2018, 23 (3) 204-207; DOI: https://doi.org/10.17712/nsj.2018.3.20180003
Hind A. Alnajashi
From the Neurology Division (Alnajashi), Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, from the Department of Neurology (Alshamrani), Imam Abdulrahman Bin Faisal University, King Fahad Hospital of the University, Dammam, and from the Neurology Division (Freedman) Department of Medicine, University of Ottawa, and the Ottawa Hospital Research Institute, Ottawa, Canada
MD, SBN
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  • For correspondence: [email protected]
Foziah J. Alshamrani
From the Neurology Division (Alnajashi), Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, from the Department of Neurology (Alshamrani), Imam Abdulrahman Bin Faisal University, King Fahad Hospital of the University, Dammam, and from the Neurology Division (Freedman) Department of Medicine, University of Ottawa, and the Ottawa Hospital Research Institute, Ottawa, Canada
MD, SBN
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Mark S. Freedman
From the Neurology Division (Alnajashi), Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, from the Department of Neurology (Alshamrani), Imam Abdulrahman Bin Faisal University, King Fahad Hospital of the University, Dammam, and from the Neurology Division (Freedman) Department of Medicine, University of Ottawa, and the Ottawa Hospital Research Institute, Ottawa, Canada
HSBc, FRCPC
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References

  1. ↵
    1. Miller AE
    (2015) Teriflunomide: a once-daily oral medication for the treatment of relapsing forms of multiple sclerosis. Clin Ther 37, 2366–2380.
  2. ↵
    1. Confavreux C,
    2. O'Connor P,
    3. Comi G,
    4. Freedman MS,
    5. Miller AE,
    6. Olsson TP,
    7. et al.
    (2014) Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Neurol 13, 247–256.
  3. ↵
    1. O'Connor P,
    2. Wolinsky JS,
    3. Confavreux C,
    4. Comi G,
    5. Kappos L,
    6. Olsson TP,
    7. et al.
    (2011) Randomized trial of oral teriflunomide for relapsing multiple sclerosis. N Engl J Med 365, 1293–12303.
  4. ↵
    1. Freedman MS
    (2013) Teriflunomide in relapsing multiple sclerosis: therapeutic utility. Ther Adv Chronic Dis 4, 192–205.
  5. ↵
    1. Oh J,
    2. O'Connor PW
    (2014) Teriflunomide in the treatment of multiple sclerosis: current evidence and future prospects. Ther Adv Neurol Disord 7, 239–252.
  6. ↵
    1. Vermersch P,
    2. Czlonkowska A,
    3. Grimaldi LM,
    4. Confavreux C,
    5. Comi G,
    6. Kappos L,
    7. et al.
    (2014) Teriflunomide versus subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis: a randomised, controlled phase 3 trial. Mult Scler 20, 705–716.
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Neurosciences Journal: 23 (3)
Neurosciences Journal
Vol. 23, Issue 3
1 Jul 2018
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Tolerability and discontinuation rates in teriflunomide-treated patients
Hind A. Alnajashi, Foziah J. Alshamrani, Mark S. Freedman
Neurosciences Journal Jul 2018, 23 (3) 204-207; DOI: 10.17712/nsj.2018.3.20180003

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Tolerability and discontinuation rates in teriflunomide-treated patients
Hind A. Alnajashi, Foziah J. Alshamrani, Mark S. Freedman
Neurosciences Journal Jul 2018, 23 (3) 204-207; DOI: 10.17712/nsj.2018.3.20180003
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© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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