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Treatment of infantile spasms in Saudi Arabia

Maryam A. Alqassas, Osama Y. Muthaffar, Anan A. Aljawi, Ahad M. Taj, Haya K. Nijaifan, Reem A. Alyoubi and Mohammed M. Jan
Neurosciences Journal July 2018, 23 (3) 258-261; DOI: https://doi.org/10.17712/nsj.2018.3.20180015

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Tables

  • Table 1

    First and second line AED choices for treating patients with infantile spasms excluding those caused by tuberous sclerosis complex. N=52

    First lineSecond line
    AEDn(%)AEDn(%)
    Vigabatrin25(48)Vigabatrin19(36.5)
    Steroids22(42)Steroids24(46)
     ACTH11(21) ACTH9(17)
     Oral11(21) Oral15(29)
    Valproic acid4(8)Topiramate5(9.5)
    Other1(2)Other4(8)

    • AED - antiepileptic drug, ACTH - adrenocorticotropic hormone

  • Table 2

    Treatment choices for resistant cases that failed first and second line AEDs.

    Treatmentn(%)
    Topiramate39(75)
    Pyridoxine37(71)
    Levetiracetam36(69)
    Valproic acid26(50)
    Clonazepam22(42)
    Oral steroids19(36)
    Ketogenic diet19(36)
    Vigabatrin13(25)
    ACTH12(23)
    IVIG5(10)

    • ACTH - adrenocorticotropic hormone, IVIG - intravenous immunoglobulin

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