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Research ArticleOriginal Article
Open Access

Pediatric intracranial hypertension

Experience from 2 Tertiary Centers

Fahad A. Bashiri, Hissah K. Al Abdulsalam, Saeed M. Hassan, Waleed A. Al Twaijri, Fuad I. Almalki, Amal Y. Kentab, Muddathir H. Hamad, Ali H. Alwadei, Daniah A. Al-Showaeir, Ikhlass S. Altweijri, Haifa M. Aldabjan, Moudi S. Aldegether, Abdulrahman A. Albakr, Wajda M. Alhothali, Abdulrazag M. Ajlan, Hamdy H. Hassan and Mustafa A. Salih
Neurosciences Journal October 2019, 24 (4) 257-263; DOI: https://doi.org/10.17712/nsj.2019.4.20190052
Fahad A. Bashiri
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Hissah K. Al Abdulsalam
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Saeed M. Hassan
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Waleed A. Al Twaijri
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Fuad I. Almalki
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Amal Y. Kentab
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Muddathir H. Hamad
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Ali H. Alwadei
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Daniah A. Al-Showaeir
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Ikhlass S. Altweijri
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Haifa M. Aldabjan
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Moudi S. Aldegether
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Abdulrahman A. Albakr
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Wajda M. Alhothali
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Abdulrazag M. Ajlan
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Hamdy H. Hassan
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Mustafa A. Salih
From the Division of Neurology (Bashiri, Hassan, Kentab, Hamad, Salih), Departments of Pediatrics, Department of Surgery (Al Abdulsalam, Altweijri, Aldabjan, Aldegether, Albakr, Alhothali, Ajlan), Neuro-ophthalmology Division (Al-Showaeir), Department of Ophthalmology, and from the Neuroradiology Division (Hassan), Department of Radiology, College of Medicine, King Saud University, and from Department of Pediatric Neurology (Alwadei), National Neuroscience Institute, King Fahad Medical City, and from King Abdullah Children Specialist Hospital (Al Twaijri), National Guard Health Affairs, Riyadh, and from the Department of Pediatrics (Almalki), College of Medicine, Majmaah University, Almajmaah, Kingdom of Saudi Arabia.
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Abstract

Objectives: To review the experience of 2 tertiary centers in Saudi Arabia with intracranial hypertension (IH) in the pediatric population.

Methods: We retrospectively reviewed and analyzed pediatric patients diagnosed with IH from June 2002 to May 2017 in 2 institutes.

Results: We identified 53 patients (30 females and 23 males) with a mean age of 7 years at the time of presentation. Among them, 41 patients were younger than 12 years, and 12 were older. Obese and overweight patients constituted 27.00% (n = 14) of all cases, 8 (66.7%) of whom were older than 12 years. The most common presenting feature was papilledema followed by headache. Vitamin D deficiency, which constituted the most common associated condition, was identified in 12 (22.6%) patients. Acetazolamide was the treatment option in 98.11% of patients, and only 5.7% underwent surgical interventions. The length of follow-up ranged from 6 months to 8 years.

Conclusion: Intracranial hypertension is rare in children and commonly seen in overweight females older than 12 years similar to adults. Patients younger than 12 years tend to develop secondary IH. More studies are needed to characterize the clinical presentation and guide the management plan.

Footnotes

  • Disclosure. Authors have no conflict of interests, and the work was not supported or funded by any drug company.

  • Received June 12, 2019.
  • Accepted August 13, 2019.
  • Copyright: © Neurosciences

Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Pediatric intracranial hypertension
Fahad A. Bashiri, Hissah K. Al Abdulsalam, Saeed M. Hassan, Waleed A. Al Twaijri, Fuad I. Almalki, Amal Y. Kentab, Muddathir H. Hamad, Ali H. Alwadei, Daniah A. Al-Showaeir, Ikhlass S. Altweijri, Haifa M. Aldabjan, Moudi S. Aldegether, Abdulrahman A. Albakr, Wajda M. Alhothali, Abdulrazag M. Ajlan, Hamdy H. Hassan, Mustafa A. Salih
Neurosciences Journal Oct 2019, 24 (4) 257-263; DOI: 10.17712/nsj.2019.4.20190052

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Pediatric intracranial hypertension
Fahad A. Bashiri, Hissah K. Al Abdulsalam, Saeed M. Hassan, Waleed A. Al Twaijri, Fuad I. Almalki, Amal Y. Kentab, Muddathir H. Hamad, Ali H. Alwadei, Daniah A. Al-Showaeir, Ikhlass S. Altweijri, Haifa M. Aldabjan, Moudi S. Aldegether, Abdulrahman A. Albakr, Wajda M. Alhothali, Abdulrazag M. Ajlan, Hamdy H. Hassan, Mustafa A. Salih
Neurosciences Journal Oct 2019, 24 (4) 257-263; DOI: 10.17712/nsj.2019.4.20190052
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© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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