Prevalence of antidepressant-induced sexual dysfunction among psychiatric outpatients attending a tertiary care hospital

Article Figures & Data

Table 1

Patients’ demographic characteristics.

Factor	n (%)
*Age (years)*
18-40	89 (65.0)
41-60	37 (27.0)
>60	11 (8.0)
*Sex*
Female	71 (51.0)
Male	66 (49.0)
*Marital status*
Single	37 (27.0)
Married	93 (67.8)
Other	7 (5.1)
*Diagnosis*
Depression	62 (45.0)
Anxiety disorders	49 (36.0)
Obsessive Compulsive Disorder	21 (15.3)
Other	5 (3.7)

Table 4

Rate (w%) of sexual dysfunction among participants per antidepressant.

	Fluoxetine (%)	Mirtazapine(%)	Paroxetine(%)	Venlafaxine(%)	p-value^*
Decreased libido	(29.4)	(28.0)	(59.6)	(47.0)	0.189
Increased libido	(26.4)	(21.8)	(25.0)	(29.4)	0.996
Premature ejaculation	(33.3)	(46.1)	(62.0)	(77.0)	0.466
Delayed ejaculation	(22.2)	(30.7)	(34.4)	(22.2)	0.909
Anorgasmia	(35.2)	(28.1)	(48.0)	(52.9)	0.240
Erectile dysfunction	(27.7)	(38.4)	(44.8)	(44.4)	0.635

↵* Pearson chi-square test was used to test the relationship between the 2 variables and the differences was considered statistically significant if the p-value <0.05

Antidepressant	n	Average dose in mg(SD)	Mean duration of use in years (SD)
Paroxetine	52	22.3 (8.4)	5.1 (3.2)
Fluoxetine	36	25.5 (9.0)	2.7 (8.1)
Mirtazapine	32	20.4 (9.3)	3.3 (3.9)
Venlafaxine	17	94.8 (49.8)	4.5 (0.7)

Symptoms	Male	Female	P-value ^*
Symptoms	n (%)		P-value ^*
Increased libido	39 (59.0)	27 (38.0)	0.001
Decreased libido	46 (69.6)	38 (53.5)	0.265
Anorgasmia	45 (68.1)	37 (52.1)	0.054