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Research ArticleOriginal Article
Open Access

Right-Sided clinical findings are worse prognostic factor in Multiple Sclerosis patients?

Asuman O. Varoglu and Ece Balkuv
Neurosciences Journal April 2020, 25 (2) 97-103; DOI: https://doi.org/10.17712/nsj.2020.2.20190111
Asuman O. Varoglu
From the Department of Neurology, Medical Faculty, Istanbul Medeniyet University, Istanbul, Turkey.
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  • For correspondence: [email protected]
Ece Balkuv
From the Department of Neurology, Medical Faculty, Istanbul Medeniyet University, Istanbul, Turkey.
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Article Figures & Data

Tables

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    Table 1

    The demographic features of multiple sclerosis patients.

    Age (year)n (%)
    Min-Max (Median)19-69 (40)
    m±SD40.70±10.05
    Gender n (%)
    Female251 (69.5)
    Male110 (30.5)
    Duration of illness (year)
    Min-Max (Median)1-43 (8)
    m±SD10.98±7.94
    Age of onset of illness (year)
    Min-Max (Median)14-58 (29)
    m±SD30.42±8.70
    Educationstatus n (%)
    Noliterate14 (3,8)
    Primaryschool170 (47.1)
    High school95 (26.4)
    License74 (20.5)
    Graduate8 (2.2)
    Familyhistory n (%)
    MS absent336 (93.1)
    First degreerelative20 (5.5)
    Second degreerelative5 (1.4)
    • View popup
    Table 2

    Evaluating of EDSS, PI and MSSS only at the first attacks in MS patients.

    EDSSRight sidedLeft sidedBilateral sidedap-value
    n=78n=11n=6n=53
    Min-Max(Median)1-6.5 (2)1-5 (2.3)0-7 (1.5)0.347
    Mean±SD2.59±1.432.75±1.472.50±2.26
    PI
    Min-Max(Median)0.2-3.3 (1)0.1-2 (1)0-5 (0.3)0.016*
    Mean±SD1.33±1.071.13±0.750.65±0.87
    MSSS
    Min-Max(Median)18-96 (67)32-90 (37)0-96 (31)0.214
    Mean±SD56.64±26.4552.80±26.9641.5±32.71
    • ↵a Kruskall Wallis Test

    • ↵* p<0.05

    • View popup
    Table 3

    Evaluation of EDSS, PI and MSSS Value of Side of Clinical Findings in the Remission and Attack Periods at the first and last attacks.

    The First attack side of clinical findingsaP-valueThe Last attack side of clinical findingsaP-value
    Right (n=36)Left (n=39)Bilateral (n=183)Right(n=8)Left(n=7)Bilateral (n=259)
    EDSS
    RemissionMin-Max(Median)0-4.5 (1)0-7 (1.5)0-8 (1.5)0.1231-3.5 (2)1-6.5 (2)0-8 (1.5)0.139
    Mean±SD1.47±1.222.24±1.752.29±2.042.14±1.033.29±2.272.12±1.88
    AttackMin-Max(Median)0-4 (2)0-7 (2)0-8.5 (2)0.8601-5.5 (2.5)1-5 (3)0-8.5 (2)0.191
    Mean±SD1.93±0.912.40±1.802.46±2.082.88±1.602.93±1.482.34±1.92
    bp-value0.0570.6600.2240.042*1.0000.058
    Difference (Attack-Remission)Min-Max(Median)−2.5-3 (0.5)−5-7 (0)−6.5-6 (0)0.6300-2 (1)−5-2 (0)−6.5-7 (0)0.331
    Mean±SD0.46±1.350.15±2.190.18±2.401.00±0.87−0.36±2.390.22±2.24
    PI
    RemissionMin-Max(Median)0-2 (0.3)0-3.5 (1)0-6.5 (0.5)0.1260.3-3 (1)0.3-6.5 (0.7)0-5.5 (0.5)0.078
    Mean±SD0.66±0.700.93±0.790.75±0.891.29±0.861.47±2.230.75±0.78
    AttackMin-Max(Median)0-3 (1)0-4 (0.6)0-6.5 (0.3)0.001**0.3-5 (0.8)0.2-1.5 (0.4)0-6.5 (0.4)0.350
    Mean±SD1.16±0.891.06±1.020.62±0.791.30±1.560.63±0.470.79±0.90
    bp-value0.008**0.7120.036*1.0000.0680.804
    Difference (Attack - Remission)Min-Max(Median)−1.8-2.5 (0.5)−3.1-2.4 (0)−5.5-5 (0)0.002**−1.6-2 (0.1)−5-0 (−0.1)−5.5-5 (0)0.385
    Mean±SD0.50±1.040.11±1.21−0.13±1.040.02±1.17−0.85±1.850.04±1.08
    MSSS
    RemissionMin-Max(Median)0-81 (32)10-93 (50)0-94 (36)0.007**30-88 (50)12-92 (50)0-94 (36.5)0.432
    Mean±SD35.29±21.6953.90±26.141.83±26.0757.00±25.8548.33±32.9543,29±25,77
    AttackMin-Max(Median)8-90 (50)10-93 (42)0-93 (36)0.06630-93 (70.5)12-88 (50)0-93 (37)0.071
    Mean±SD50.69±24.5352.24±25.9243.13±26.9368.13±22.0049.86±30.7345,92±26,83
    bp-value0.017*0.5810.4500.027*0.5930.153
    Difference (Attack - Remission)Min-Max(Median)−45-73 (19)−61-83 (−2)−91-81 (0)0.045*0-50 (9)−42-25 (0)−91-83 (0)0.290
    Mean±SD15.40±33.13−0.84±34.661.55±31.8016.57±17.33−3.33±21.593.20±33.48
    • ↵a Kruskall Wallis Test

    • ↵b WilcoxonSignedRanks Test

    • ↵* p<0.05

    • ↵** p<0.01

    • EDSS - Expanded Disability Status Scale

    • PI - Progression Index

    • MSSS - Multiple Sclerosis Severity Score

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Right-Sided clinical findings are worse prognostic factor in Multiple Sclerosis patients?
Asuman O. Varoglu, Ece Balkuv
Neurosciences Journal Apr 2020, 25 (2) 97-103; DOI: 10.17712/nsj.2020.2.20190111

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Right-Sided clinical findings are worse prognostic factor in Multiple Sclerosis patients?
Asuman O. Varoglu, Ece Balkuv
Neurosciences Journal Apr 2020, 25 (2) 97-103; DOI: 10.17712/nsj.2020.2.20190111
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