The role of brain magnetic resonance imaging on the timing of antiepileptic drugs withdrawal following mesial temporal lobe epilepsy surgery

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Figure 1
- Characteristics of MRI brain findings.
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Figure 2
- Correlation of seizures retiming of seizures and patient characteristics (*indicated p-value<0.05).

Table 1

- Seizure outcomes after anterior temporal lobectomy.

Characteristic	No seizures off medication n=23	No seizures on medication n=24	Seizures on medication n=17	P-value
Sex (male)	16 (70%)	11 (46%)	12 (71%)	NS
Mean age at epilepsy surgery	33 years	36 years	32 years	NS
Baseline median of monthly seizures	4	4	4.25	NS
Presence of febrile convulsions	11 (48%)	6 (25%)	5 (29%)	NS
Median number of AEDs	2	2.5	2	NS
Mean time to start tapering AEDs	7 months	10 months	24 months	<0.01
Mean time to discontinue AEDs	24 months	60 months	72 months	<0.01
MRI (Abnormal)	23 (100%)	21 (88%)	9 (53%)	<0.01^¹
EEG (Unilateral IEDs)	21 (91%)	16 (67%)	9 (53%)	<0.01^²
MTS in pathology	15 (65%)	14 (58%)	11 (65%)	NS