Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • Saudi Medical Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Neurosciences Journal
  • Other Publications
    • Saudi Medical Journal
  • My alerts
  • Log in
Neurosciences Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

Comparative effectiveness of dual antiplatelet therapy versus monotherapy in patients with ischemic stroke

Rahmah A. Algarni, Abdulhamid A. Althagafi, Samah Alshehri, Mohannad Alshibani and Omar Alshargi
Neurosciences Journal October 2023, 28 (4) 220-226; DOI: https://doi.org/10.17712/nsj.2023.4.20230021
Rahmah A. Algarni
From the Department of Pharmacy (Algarni), King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, from the Department of Pharmacy Practice (Althagafi, Alshehri, Alshibani), Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, and from the College of Pharmacy (Alshargi), Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia.
PharmD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rahmah A. Algarni
  • For correspondence: [email protected]
Abdulhamid A. Althagafi
From the Department of Pharmacy (Algarni), King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, from the Department of Pharmacy Practice (Althagafi, Alshehri, Alshibani), Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, and from the College of Pharmacy (Alshargi), Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia.
PharmD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Samah Alshehri
From the Department of Pharmacy (Algarni), King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, from the Department of Pharmacy Practice (Althagafi, Alshehri, Alshibani), Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, and from the College of Pharmacy (Alshargi), Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia.
PharmD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mohannad Alshibani
From the Department of Pharmacy (Algarni), King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, from the Department of Pharmacy Practice (Althagafi, Alshehri, Alshibani), Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, and from the College of Pharmacy (Alshargi), Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia.
PharmD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Omar Alshargi
From the Department of Pharmacy (Algarni), King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, from the Department of Pharmacy Practice (Althagafi, Alshehri, Alshibani), Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, and from the College of Pharmacy (Alshargi), Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia.
MPharm
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Tadi Prasanna FL
    . Acute Stroke. [Updated 2023 Feb 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan [Internet]. 2023 [cited 2023 May 26]. p. 88–100.
  2. 2.↵
    1. Muhammad AT,
    2. Aljohani MM
    . Stroke In KSA ; Epidemiology And Clinical Delineation. Majmaah J Heal Sci 2021; 9: 109–120.
    OpenUrl
  3. 3.↵
    1. Franziska H,
    2. Fred R
    . Management of Acute Ischemic Stroke. Concise Defin Rev 2020; 48: 1654–1663.
    OpenUrl
  4. 4.↵
    1. Edward CJ
    . Ischemic stroke [Internet]. Medical Crossfire. 2022 [cited 2023 May 26]. Available from: https://emedicine.medscape.com/article/1916852-overview
  5. 5.↵
    1. Yiping C,
    2. Neil W,
    3. Yu G,
    4. Iain T,
    5. Christiana K,
    6. Ling Y, et al.
    Mortality and recurrent vascular events after first incident stroke: a 9-year community-based study of 0·5 million Chinese adults. Lancet Glob Heal 2020; 8: e580–e590.
    OpenUrl
  6. 6.↵
    1. Stahmeyer JT,
    2. Stubenrauch S,
    3. Geyer S,
    4. Weissenborn K,
    5. Eberhard S
    . The Frequency and Timing of Recurrent Stroke. Dtsch Arztebl Int 2019; 116: 711–717.
    OpenUrl
  7. 7.↵
    1. Kleindorfer DO,
    2. Towfighi A,
    3. Chaturvedi S,
    4. Cockroft KM,
    5. Gutierrez J,
    6. Lombardi-Hill D, et al.
    2021 Guideline for the prevention of stroke in patients with stroke and transient ischemic attack; A guideline from the American Heart Association/American Stroke Association. Stroke 20211; 52: e364–e467.
  8. 8.↵
    1. Jourdi G,
    2. Godier A,
    3. Lordkipanidzé M,
    4. Marquis-Gravel G,
    5. Gaussem P
    . Antiplatelet Therapy for Atherothrombotic Disease in 2022—From Population to Patient-Centered Approaches. Front Cardiovasc Med 2022; 9: 1–19.
    OpenUrl
  9. 9.
    1. Del Giovane C,
    2. Boncoraglio GB,
    3. Bertù L,
    4. Banzi R,
    5. Tramacere I
    . Antiplatelet drugs for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis. BMC Neurol 2021; 21: 1–10.
    OpenUrl
  10. 10.↵
    1. Minhas JS,
    2. Chithiramohan T,
    3. Wang X,
    4. Barnes SC,
    5. Clough RH,
    6. Kadicheeni M, et al.
    Oral antiplatelet therapy for acute ischaemic stroke (Review). Cochrane Database Syst Rev 2022; 1: 1–16.
    OpenUrl
  11. 11.↵
    1. Pace WD,
    2. Earl A,
    3. Bryant C
    . Antiplatelet Therapy for Secondary Prevention of Ischemic Stroke. Cardiovascular 2020; 45: HS8–HS12.
    OpenUrl
  12. 12.↵
    1. Dong J,
    2. Wang F,
    3. Sundararajan S
    . Use of Dual Antiplatelet Therapy following Ischemic Stroke. Stroke 2020; 51: e78–e80.
    OpenUrlPubMed
  13. 13.↵
    1. Brown DL,
    2. Levine DA,
    3. Albright K,
    4. Kapral MK,
    5. Leung LY,
    6. Reeves MJ, et al.
    Benefits and Risks of Dual Versus Single Antiplatelet Therapy for Secondary Stroke Prevention. Stroke 2021; 52: e468–e479.
    OpenUrlPubMed
  14. 14.↵
    1. Wang Y,
    2. Johnston C,
    3. Bath PM,
    4. Meng X,
    5. Jing J,
    6. Xie X, et al.
    Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): Rationale and design of a multicentre randomised trial. Stroke Vasc Neurol 2021; 6: 280–285.
    OpenUrlAbstract/FREE Full Text
  15. 15.↵
    1. Powers WJ,
    2. Rabinstein AA,
    3. Ackerson T,
    4. Adeoye OM,
    5. Bambakidis NC,
    6. Becker K, et al.
    Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2019; 50: e344–e418.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Pessoa RLC,
    2. Antunes-foschini R,
    3. Rocha EM
    . Survival analysis (Kaplan-Meier curves): a method to predict the future. Arq Bras Oftalmol 2020; 83: 33–35.
    OpenUrl
  17. 17.↵
    1. Deo SV
    . Survival analysis — part 2 : Cox proportional hazards model. Indian J Thorac Cardiovasc Surg 2021; 37: 229–233.
    OpenUrl
  18. 18.↵
    1. Lee HL,
    2. Kim JT,
    3. Lee JS,
    4. Park MS,
    5. Choi KH,
    6. Cho KH, et al.
    Comparative Effectiveness of Dual Antiplatelet Therapy With Aspirin and Clopidogrel Versus Aspirin Monotherapy in Mild-to-Moderate Acute Ischemic Stroke According to the Risk of Recurrent Stroke: An Analysis of 15 000 Patients From a Nationwide, Multicent. Circ Cardiovasc Qual Outcomes 2020; 13: e006474.
    OpenUrl
  19. 19.↵
    1. Hackam DG,
    2. Spence JD
    . Antiplatelet therapy in ischemic stroke and transient ischemic attack: An overview of major trials and meta-analyses. Stroke 2019; 50: 773–778.
    OpenUrlPubMed
PreviousNext
Back to top

In this issue

Neurosciences Journal: 28 (4)
Neurosciences Journal
Vol. 28, Issue 4
1 Oct 2023
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Neurosciences Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Comparative effectiveness of dual antiplatelet therapy versus monotherapy in patients with ischemic stroke
(Your Name) has sent you a message from Neurosciences Journal
(Your Name) thought you would like to see the Neurosciences Journal web site.
Citation Tools
Comparative effectiveness of dual antiplatelet therapy versus monotherapy in patients with ischemic stroke
Rahmah A. Algarni, Abdulhamid A. Althagafi, Samah Alshehri, Mohannad Alshibani, Omar Alshargi
Neurosciences Journal Oct 2023, 28 (4) 220-226; DOI: 10.17712/nsj.2023.4.20230021

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Comparative effectiveness of dual antiplatelet therapy versus monotherapy in patients with ischemic stroke
Rahmah A. Algarni, Abdulhamid A. Althagafi, Samah Alshehri, Mohannad Alshibani, Omar Alshargi
Neurosciences Journal Oct 2023, 28 (4) 220-226; DOI: 10.17712/nsj.2023.4.20230021
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • The association between cigarette smoking and sleep deprivation among adolescents in Gulf Cooperation Council countries: analysis of national surveys
  • Motherhood and pregnancy concerns of Saudi females with multiple sclerosis in Riyadh city: A quantitative analysis
  • Ranking the difficulty of the cognitive tasks in Dual-Tasks during walking in healthy adults
Show more Original Article

Similar Articles

Navigate

  • home

More Information

  • Help

Additional journals

  • All Topics

Other Services

  • About

© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

Powered by HighWire