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Case ReportCase Report
Open Access

Hemorrhagic fever with renal syndrome and reversible splenial lesion syndrome

Xulei Zhang, Yimin Ma, Renchen Cai and Zhenguo Qiao
Neurosciences Journal October 2023, 28 (4) 270-272; DOI: https://doi.org/10.17712/nsj.2023.4.202300133
Xulei Zhang
From the Department of Infection (Zhang), Department of Gastroenterology (Ma), Department of Geriatrics (Cai), Gaochun People’s Hospital, Nanjing, and From the Department of Gastroenterology (Qiao), Suzhou Ninth People’s Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.
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Yimin Ma
From the Department of Infection (Zhang), Department of Gastroenterology (Ma), Department of Geriatrics (Cai), Gaochun People’s Hospital, Nanjing, and From the Department of Gastroenterology (Qiao), Suzhou Ninth People’s Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.
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Renchen Cai
From the Department of Infection (Zhang), Department of Gastroenterology (Ma), Department of Geriatrics (Cai), Gaochun People’s Hospital, Nanjing, and From the Department of Gastroenterology (Qiao), Suzhou Ninth People’s Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.
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Zhenguo Qiao
From the Department of Infection (Zhang), Department of Gastroenterology (Ma), Department of Geriatrics (Cai), Gaochun People’s Hospital, Nanjing, and From the Department of Gastroenterology (Qiao), Suzhou Ninth People’s Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.
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  • For correspondence: [email protected]
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    Figure 1

    - On the day of admission, MRI (a-e) showed areas of high-signal-intensity on T2WI, FLAIR, and DWI. And after effective treatments, follow-up MRI (f-j) revealed significant regression of the lesion in SCC.

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    Table 1

    - Abnormal indicators of peripheral blood analysis.

    Days123510Normal range
    WBC (× 109/L)7.2533.8923.2811.38.093.5-9.5
    N (%)89.97478.68478.150-70
    PLT (×109/L)877132898100-300
    CRP (mg/L)62.3472.3868.1650.44157.760-10
    PCT (ng/mL)8.4230.4123.6612.920.910-0.05
    BNP (pg/ml)374.842253.65832.96736.81869.30-125
    Na+ (mmol/L)120.8128129.4137136136-145
    PT (sec)14.213.61315.213.310.4-14.5
    D-Dimer (ng/mL)13.861.151.882.855.850-0.5
    Fibrinogen (g/L)2.571.591.752.245.462-4
    SCR (µmol/L)-29436921342158-110
    BUN (mmol/L)-18.5223.313.418.573.2-7.1
    Plasma lactate (mmol/L)3.264.831.21.10.70.7-2.1
    K+ (mmol/L)3.073.443.753.53.23.5-5.5
    ALT (U/L)-834236290-50
    AST (U/L)1192181381052417-59
    • WBC - White blood cell count, N - Neutrophils, PLT - Platelet, CRP - C-reactive protein, PCT - Procalcitonin, BNP - N-terminal-pro-B-type natriuretic peptide, Na+ - Blood sodium, PT - Plasma prothrombin time, SCR - Serum creatinine, BUN - Blood urea nitrogen, K+ - Blood potassium, ALT - Alanine amino transferase, AST - Antarctic submillimeter telescope

    • View popup
    Table 2

    - Timeline table.

    DateEvent
    Day 1Fever, dizziness
    Day 3Slurred speech, muscle weakness with instability, and difficulty in walking
    Day 4MRI showed hyperintensity in the splenium of the corpus callosum.
    Day 5Mild abnormal renal function
    Day 6Systemic inflammatory response severe thrombocytopenia
    Day 16Renal function recovery
    Day 20Discharge
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Neurosciences Journal: 28 (4)
Neurosciences Journal
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Hemorrhagic fever with renal syndrome and reversible splenial lesion syndrome
Xulei Zhang, Yimin Ma, Renchen Cai, Zhenguo Qiao
Neurosciences Journal Oct 2023, 28 (4) 270-272; DOI: 10.17712/nsj.2023.4.202300133

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Hemorrhagic fever with renal syndrome and reversible splenial lesion syndrome
Xulei Zhang, Yimin Ma, Renchen Cai, Zhenguo Qiao
Neurosciences Journal Oct 2023, 28 (4) 270-272; DOI: 10.17712/nsj.2023.4.202300133
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