Abstract
OBJECTIVE: The metaphase of 21 severely mentally retarded patients were studies to assess the role of satellite association in the etiology of mental retardation.
METHODS: Peripheral blood culture, chromosome harvesting and study scoring were conducted according to standard methods.
RESULTS: Considered as a whole the results indicate that there is a significant increase in the frequency of satellite association among the mentally retarded.
CONCLUSION: The present study concluded that satellite association may play a role in the etiology of mental retardation and may explain to some extent the presence of normal karyotype in some mental retardation patients.
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