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Review ArticleREVIEW ARTICLES
Open Access

An evidence-based review of Dopamine receptor agonists in the treatment of Parkinson’s disease

Dirk Deleu, Margaret G. Northway and Yolande Hanssens
Neurosciences Journal October 2002, 7 (4) 221-231;
Dirk Deleu
College of Medicine, Sultan Qaboos University, PO Box 35, Al Khod, PC-123, Sultanate of Oman. Tel. +968 515106. Fax. +968 513419. E-mail: [email protected]
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  • For correspondence: [email protected]
Margaret G. Northway
College of Medicine, Drug Information Services, Sultan Qaboos University Hospital, Sultanate of Oman.
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Yolande Hanssens
College of Pharmacy, Drug Information Services, Sultan Qaboos University Hospital, Sultanate of Oman.
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Abstract

Apomorphine and certain ergot alkaloids (bromocriptine, lisuride and pergolide) have been available for several decades; for the last few years, they were joined by newer dopamine agonists (cabergoline, pramipexole and ropinirole) most of them are non-ergolines. Each of these dopamine agonists has its own pharmacological characteristics and occupies a place in the pharmacotherapy of Parkinsons disease. In this evidence-based review, emphasis is put on the clinical efficacy of dopamine agonists in early and advanced Parkinsons disease, and where possible comparative evidence regarding their efficacy and safety is provided. In addition, their clinical pharmacokinetics, adverse effect profiles and most relevant interactions will be summarized.

  • Copyright: © Neurosciences

Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Neurosciences Journal: 7 (4)
Neurosciences Journal
Vol. 7, Issue 4
1 Oct 2002
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An evidence-based review of Dopamine receptor agonists in the treatment of Parkinson’s disease
Dirk Deleu, Margaret G. Northway, Yolande Hanssens
Neurosciences Journal Oct 2002, 7 (4) 221-231;

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An evidence-based review of Dopamine receptor agonists in the treatment of Parkinson’s disease
Dirk Deleu, Margaret G. Northway, Yolande Hanssens
Neurosciences Journal Oct 2002, 7 (4) 221-231;
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© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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