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Research ArticleOriginal Article
Open Access

Length of MRI signal may predict outcome in advanced cervical spondylotic myelopathy

Amro F. Al-Habib, Ahmed M. AlAqeel, Abdulrahman S. Aldakkan, Fahad B. AlBadr and Shaffi A. Shaik
Neurosciences Journal January 2015, 20 (1) 41-47;
Amro F. Al-Habib
From the Division of Neurosurgery (Al-Habib, AlAqeel, Aldakkan), Department of Surgery, the Departments of Radiology (AlBadr), and Family and Community Medicine (Shaik), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
MD, FRCSC
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  • For correspondence: [email protected]
Ahmed M. AlAqeel
From the Division of Neurosurgery (Al-Habib, AlAqeel, Aldakkan), Department of Surgery, the Departments of Radiology (AlBadr), and Family and Community Medicine (Shaik), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
MD
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Abdulrahman S. Aldakkan
From the Division of Neurosurgery (Al-Habib, AlAqeel, Aldakkan), Department of Surgery, the Departments of Radiology (AlBadr), and Family and Community Medicine (Shaik), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
MD
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Fahad B. AlBadr
From the Division of Neurosurgery (Al-Habib, AlAqeel, Aldakkan), Department of Surgery, the Departments of Radiology (AlBadr), and Family and Community Medicine (Shaik), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
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Shaffi A. Shaik
From the Division of Neurosurgery (Al-Habib, AlAqeel, Aldakkan), Department of Surgery, the Departments of Radiology (AlBadr), and Family and Community Medicine (Shaik), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
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  • Figure 1
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    Figure 1

    Measurements for the anterior posterior diameter of the cervical spinal canal.

  • Figure 2
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    Figure 2

    Preoperative T2WI sagittal MRI showing increased signal intensity (ISI). A) Type 1: faint ISI with fuzzy border (arrow). B) Type 2: intense ISI with well-defined border (arrow).

  • Figure 3
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    Figure 3

    Nurick grade for all advanced cervical spondylotic myelopathy patients at latest follow-up. Among patients with pre-operative Nurick grade 5, 36.4% remained the same, 27.3% improved to Nurick 4 grade, and the rest (36.3%) had a Nurick grade from 1 to 3. On the other hand, among those with pre-operative Nurick grade of 4, only 14.3% remained the same while 85.7% improved to Nurick grade 1-3.

Tables

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    Table 1

    Nurick classification of disability in cervical spondylotic myelopathy.

    Grade 0Root signs and symptoms. No evidence of spinal cord involvement
    Grade 1Signs of spinal cord involvement, but no difficulty walking
    Grade 2Slight difficulty walking that does not prevent full-time employment
    Grade 3Difficulty walking that prevents full-time employment or the ability to perform all housework, but that was not severe enough to require someone else help to walk
    Grade 4Able to walk with someone else’s help or the aid of a frame
    Grade 5Chair bound or bedridden
    • View popup
    Table 2

    Characteristics of advanced cervical spondylotic myelopathy patients (N=43).

    VariableNurick 4 (n=21)Nurick 5 (n=22)P-value
    Age (mean-years)59.2464.320.130
    Surgical approach
     Anterior (n, %)14 (66.7)12 (54.5)
     Posterior (n, %)7 (33.3)10 (45.5)0.416
     Average BMI (kg)27.6122.660.584
     Smoking (n, %)14 (66.7)5 (22.7)0.004
     Comorbidity* (n, %)16 (76.2)19 (86.4)0.322
     Mean duration of difficulty in walking prior to surgery (months)6.714.230.008
     Walking independently after surgery** (n, %)18 (85.7)8 (36.4)0.001
    Preoperative MRI features7-13:
     T1WI signal change (n, %)6 (28.6)11 (50.0)0.151
    Type of T2WI signal intensity: (n, %)
     Type 02 (9.5)0 (0.0)0.233
     Type 113 (61.9)16 (72.7)0.449
     Type 26 (28.6)6 (27.3)0.924
    Average length of signal change on T2WI (mm)8.5518.000.005
    Average AP spinal canal size (mm)***7.2386.9550.152
    • ↵* Comorbidity defined as a disease or condition that coexists with a primary disease but also stands on its own as a specific disease (for example, hypertension, diabetes mellitus),

    • ↵** Walking independently after surgery: Nurick grade 0-3.

    • ↵*** AP - Antero-posterior spinal canal size was calculated at the narrowest point of the space available for the cord at the site of maximum compression (mm).

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    Table 3

    Previous studies on the surgical results of patients with advanced cervical myelopathy.

    StudyNurick gradenMean follow-up (months)Improvement rate (%)*Ability to walk independently after surgery (%)**
    Ebersold et al 1995364788.257.1457.1
    Macdonald et al 1997184831.050.050.0
    5831.050.050.0
    Matsunaga et al 200415439211.2--
    531211.216.2-
    Rajshekhar and Kumar 20051445536.368.568.5
    51736.3100.047.0
    Scardino et al 201075953.466.622.2
    Current study42126.085.785.7
    52232.063.636.3
    • ↵* Improvement rate - percentage of patients improving by at least one Nurick grade.

    • ↵** Walk independently - Nurick scores 0-3

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Length of MRI signal may predict outcome in advanced cervical spondylotic myelopathy
Amro F. Al-Habib, Ahmed M. AlAqeel, Abdulrahman S. Aldakkan, Fahad B. AlBadr, Shaffi A. Shaik
Neurosciences Journal Jan 2015, 20 (1) 41-47;

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Length of MRI signal may predict outcome in advanced cervical spondylotic myelopathy
Amro F. Al-Habib, Ahmed M. AlAqeel, Abdulrahman S. Aldakkan, Fahad B. AlBadr, Shaffi A. Shaik
Neurosciences Journal Jan 2015, 20 (1) 41-47;
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