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Research ArticleOriginal Article
Open Access

Effects of thymoquinone, the major constituent of Nigella sativa seeds, on penicillin-induced epileptiform activity in rats

Ersin Beyazcicek, Seyit Ankarali, Ozge Beyazcicek, Handan Ankarali, Serif Demir and Recep Ozmerdivenli
Neurosciences Journal April 2016, 21 (2) 131-137; DOI: https://doi.org/10.17712/nsj.2016.2.20150781
Ersin Beyazcicek
From the Departments of Physiology (Beyazcicek E, Ankarali S, Beyazcicek O, Demir, Ozmerdivenli), and Biostatistics (Ankarali H), Medical School, Duzce University, Duzce, Turkey
MSci
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Seyit Ankarali
From the Departments of Physiology (Beyazcicek E, Ankarali S, Beyazcicek O, Demir, Ozmerdivenli), and Biostatistics (Ankarali H), Medical School, Duzce University, Duzce, Turkey
MD
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  • For correspondence: [email protected]
Ozge Beyazcicek
From the Departments of Physiology (Beyazcicek E, Ankarali S, Beyazcicek O, Demir, Ozmerdivenli), and Biostatistics (Ankarali H), Medical School, Duzce University, Duzce, Turkey
MSci
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Handan Ankarali
From the Departments of Physiology (Beyazcicek E, Ankarali S, Beyazcicek O, Demir, Ozmerdivenli), and Biostatistics (Ankarali H), Medical School, Duzce University, Duzce, Turkey
PhD
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Serif Demir
From the Departments of Physiology (Beyazcicek E, Ankarali S, Beyazcicek O, Demir, Ozmerdivenli), and Biostatistics (Ankarali H), Medical School, Duzce University, Duzce, Turkey
PhD
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Recep Ozmerdivenli
From the Departments of Physiology (Beyazcicek E, Ankarali S, Beyazcicek O, Demir, Ozmerdivenli), and Biostatistics (Ankarali H), Medical School, Duzce University, Duzce, Turkey
PhD
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Article Information

vol. 21 no. 2 131-137
DOI 
https://doi.org/10.17712/nsj.2016.2.20150781
PubMed 
27094523

Published By 
Neurosciences Journal
Online ISSN 
1658-3183
History 
  • Received December 14, 2015
  • Accepted January 20, 2016
  • Published online November 13, 2020.

Copyright & Usage 
Copyright: © Neurosciences Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

Author Information

  1. Ersin Beyazcicek, MSci,
  2. Seyit Ankarali, MD⇑,
  3. Ozge Beyazcicek, MSci,
  4. Handan Ankarali, PhD,
  5. Serif Demir, PhD and
  6. Recep Ozmerdivenli, PhD
  1. From the Departments of Physiology (Beyazcicek E, Ankarali S, Beyazcicek O, Demir, Ozmerdivenli), and Biostatistics (Ankarali H), Medical School, Duzce University, Duzce, Turkey
  1. Address correspondence and reprint request to: Assoc. Prof. Seyit Ankarali, Department of Physiology, Medical School, Duzce University, PO Box 81620, Duzce, Turkey. E-mail address: seyitankarali{at}hotmail.com
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    J. K. Akintunde, A. E. Irondi, E. O. Ajani, T. V. Olayemi
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  • Thymoquinone Potentiates the Effect of Phenytoin against Electroshock-Induced Convulsions in Rats by Reducing the Hyperactivation of m-TOR Pathway and Neuroinflammation: Evidence from In Vivo, In Vitro and Computational Studies
    Faheem Hyder Pottoo, Mohammed Salahuddin, Firdos Alam Khan, Fadhel Alomar, Marwa Abdullah AL Dhamen, Abrar Fouad Alhashim, Hawra Hussain Alqattan, Mohamed S. Gomaa, Mohammad N. Alomary
    Pharmaceuticals 2021 14 11
  • Trio-Drug Combination of Sodium Valproate, Baclofen and Thymoquinone Exhibits Synergistic Anticonvulsant Effects in Rats and Neuro-Protective Effects in HEK-293 Cells
    Faheem Hyder Pottoo, Mohammed Salahuddin, Firdos Alam Khan, Batool Taleb Albaqshi, Mohamed S. Gomaa, Fatima S. Abdulla, Noora AlHajri, Mohammad N. Alomary
    Current Issues in Molecular Biology 2022 44 10
  • Effects of Sinapic Acid on Penicillin-Induced Epileptiform Activity in Rats
    A. Coskun, E. Beyazcicek, O. Beyazcicek, A. Gok
    Neurophysiology 2022 54 3-4
  • The effect of a mixture of Nigella sativa and Thymus vulgaris extracts in children with refractory epilepsies: A randomized trial
    Ali Akbar Momen, Ali Asghar Hemati, Gholamreza Houshmand, Maryam Heydar Azadzadeh, Reza Azizi Malamiri
    Journal of Herbal Medicine 2019 15
  • Herbal Medicines for Seizures
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    Alternative and Complementary Therapies 2018 24 6
  • Investigation of the Effect of Propolis on Penicillin Induced Epileptiform Activity in Rats
    Ersin BEYAZÇİÇEK
    Medical Records 2023 5 Supplement (1)
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    Habibullah Khalilullah
    2018
  • Biochemistry, Nutrition, and Therapeutics of Black Cumin Seed
    Hakan Ak, İsmail GÜLŞEN, İhsan CANBEK
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  • Effects of chronic administration of thymoquinone on penicillin induced epileptiform activity in rats
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    Anadolu Kliniği Tıp Bilimleri Dergisi 2023 28 1
  • Evaluation of the Cytotoxic Efficacy of Thymoquinone and Capsaicin in the SH-SY5Y Neuroblastoma Cell Line
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    International Journal of Nature and Life Sciences 2022 6 2
  • Investigation of the Antiepileptic Effect of (R)-(-) and (S)-(+) Carvone in Penicillin-Induced Epileptiform Activity Model
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Effects of thymoquinone, the major constituent of Nigella sativa seeds, on penicillin-induced epileptiform activity in rats
Ersin Beyazcicek, Seyit Ankarali, Ozge Beyazcicek, Handan Ankarali, Serif Demir, Recep Ozmerdivenli
Neurosciences Journal Apr 2016, 21 (2) 131-137; DOI: 10.17712/nsj.2016.2.20150781

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Effects of thymoquinone, the major constituent of Nigella sativa seeds, on penicillin-induced epileptiform activity in rats
Ersin Beyazcicek, Seyit Ankarali, Ozge Beyazcicek, Handan Ankarali, Serif Demir, Recep Ozmerdivenli
Neurosciences Journal Apr 2016, 21 (2) 131-137; DOI: 10.17712/nsj.2016.2.20150781
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© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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