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Research ArticleOriginal Article
Open Access

Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients

Veli Caglar, Selen I. Alp, Berrin T. Demir, Umit Sener, Oguz A. Ozen and Recep Alp
Neurosciences Journal April 2016, 21 (2) 145-150; DOI: https://doi.org/10.17712/nsj.2016.2.20150783
Veli Caglar
From the Departments of Anatomy (Caglar, Ozen), Physiology (Sener), and Neurology (Alp R), Faculty of Medicine, and the Vocational School of Health Service (Alp S), Namik Kemal University, Tekirdag, and the Department of Anatomy (Demir), Faculty of Medicine, Turgut Ozal University, Ankara, Turkey
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Selen I. Alp
From the Departments of Anatomy (Caglar, Ozen), Physiology (Sener), and Neurology (Alp R), Faculty of Medicine, and the Vocational School of Health Service (Alp S), Namik Kemal University, Tekirdag, and the Department of Anatomy (Demir), Faculty of Medicine, Turgut Ozal University, Ankara, Turkey
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Berrin T. Demir
From the Departments of Anatomy (Caglar, Ozen), Physiology (Sener), and Neurology (Alp R), Faculty of Medicine, and the Vocational School of Health Service (Alp S), Namik Kemal University, Tekirdag, and the Department of Anatomy (Demir), Faculty of Medicine, Turgut Ozal University, Ankara, Turkey
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  • For correspondence: [email protected]
Umit Sener
From the Departments of Anatomy (Caglar, Ozen), Physiology (Sener), and Neurology (Alp R), Faculty of Medicine, and the Vocational School of Health Service (Alp S), Namik Kemal University, Tekirdag, and the Department of Anatomy (Demir), Faculty of Medicine, Turgut Ozal University, Ankara, Turkey
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Oguz A. Ozen
From the Departments of Anatomy (Caglar, Ozen), Physiology (Sener), and Neurology (Alp R), Faculty of Medicine, and the Vocational School of Health Service (Alp S), Namik Kemal University, Tekirdag, and the Department of Anatomy (Demir), Faculty of Medicine, Turgut Ozal University, Ankara, Turkey
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Recep Alp
From the Departments of Anatomy (Caglar, Ozen), Physiology (Sener), and Neurology (Alp R), Faculty of Medicine, and the Vocational School of Health Service (Alp S), Namik Kemal University, Tekirdag, and the Department of Anatomy (Demir), Faculty of Medicine, Turgut Ozal University, Ankara, Turkey
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    Figure 1

    Measurements of the planimetry technique for the assessment of the projection areas length of the corpus callosum using ImageJ software. a) Indicates is the length of corpus callosum (L), b) the surface area of the corpus callosum, A - indicates the surface area of the corpus callosum, and L - is the length of corpus callosum.

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    Table 1

    Demographic data of the control and the patient groups.

    VariablenAge (years) mean ± SDTotal brain volume (cm3) mean ± SDP-valueCC PAL (%) mean ± SDP-value
    Groups
     Control2626.9 ± 18.3969.6 ± 68.3NS11.5 ± 2.2<0.0001
     Patients with TLE2534.2 ± 19.6941.4 ± 65.08.9 ± 2.4
    Age of control group
     < 25 years of age1817.1 ± 5.20966.1 ± 79.3NS11.6 ± 2.2NS
     ≥ 25 years of age849 ± 18977.5 ± 35.411.2 ± 2.4
    Age of patients with TLE
     < 25 years of age1017.4 ± 6.80942.2 ± 63.7NS11.6 ± 1.0<0.0001
     ≥ 25 years of age1548.0 ± 12.9940.9 ± 68.17.2 ± 1.2
    During of TLE
     <10 years1222.3 ± 13.1943.0 ± 61.3NS10.8 ± 2.0<0.0001
     ≥10 years1348.2 ± 13.9940.0 ± 70.87.2 ± 1.3
    • Values are means ± SD. CC - corpus callosum, PAL - projection area length, TLE - temporal lobe epilepsy, P-value shows comparison between 2 groups, NS - non significant

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    Table 2

    Comparison of CC PAL values and TBV in the control and patient groups.

    GroupsnCC PAL (%) mean ± SDP-valueTBV (cm3) mean ± SDP-value
    Males control group1213.3 ± 1.5<0.0001997.50 ± 71.1NS
    Male patients with TLE1110.1 ± 1.7971.50 ± 73.9
    Females control group149.9 ± 1.40.027945.79 ± 57.9NS
    Female patients with TLE148.0 ± 2.6917.50 ± 47.0
    • Values are means ± SD, CC - corpus callosum, PAL - projection area length, P-value shows comparison between 2 groups, NS - non significant

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Neurosciences Journal: 21 (2)
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Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
Veli Caglar, Selen I. Alp, Berrin T. Demir, Umit Sener, Oguz A. Ozen, Recep Alp
Neurosciences Journal Apr 2016, 21 (2) 145-150; DOI: 10.17712/nsj.2016.2.20150783

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Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
Veli Caglar, Selen I. Alp, Berrin T. Demir, Umit Sener, Oguz A. Ozen, Recep Alp
Neurosciences Journal Apr 2016, 21 (2) 145-150; DOI: 10.17712/nsj.2016.2.20150783
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