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Tables
Characteristics n (%) Mean±SD Min-Max Age (years) 18-30 24 (40) 32.55 (6.78) 18-45 31-45 36 (60) Sex Female 49 (81.7) Male 11 (18.3) Disease duration (years) 1-7 33 (55) 7 (3.45) 1-14 8-14 27 (45) Annualized relapse rate 1-4 57 (95) 1.8 (1.35) 1-8 5-8 3 (5) EDSS 0-3 30 (50) 3.3 (1.11) 1.5-6 3.5-6 30 (50) EDSS - expanded disability status scale
Study variables Before intervention After 12 months P-value Mean±SD Annualized relapse rate (attack/year) 1.8±1.35 0.27±0.58 0.001 EDSS 3.32±1.1 2.97±1.17 0.001 Lymphocyte count (no/mm3) 2262.12±874.4 729.77±227.36 0.001 WBC count (no/mm3) 7223.83±2366.03 4831.08±3462.71 0.001 ALT (mg/dl) 22.13±12.77 27.52±15.75 0.001 AST (mg/dl) 20.34±7.54 22.9±6.47 0.061 Systolic blood pressure (mmHg) 111.83±7.97 112.42±6.73 0.065 Diastolic blood pressure (mmHg) 73.83±7.56 74.15±6.10 0.062 Total cholesterol (mg/dl) 189.38±36.69 190.05±41.89 0.065 LDL cholesterol (mg/dl) 111.10±31.70 115.33±33.81 0.075 Triglyceride (mg/dl) 130.23±53.95 129±53.10 0.065 ALT - Alanine aminotransferase, AST - Aspartate aminotransferase, LDL - Low-density lipoprotein WBC - White blood cells, EDSS - Expanded disability status scale
Adverse events n (%) Upper Respiratory tract Infection 20 (3.33) Headache 10 (16.66) Urinary Tract Infection 8 (13.33) Menstrual irregularity 5 (8.33) Pneumonia 3 (5.0) Dyspnea 3 (5.0) Anxiety 2 (3.33) Influenza 1 (1.66) Dyspepsia 1 (1.66) Restless Leg Syndrome 1 (1.66) Depression 1 (1.66)