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A review of the bidirectional relationship between psychiatric disorders and diabetes mellitus

Abdulrahman A. Al-Atram
Neurosciences Journal April 2018, 23 (2) 91-96; DOI: https://doi.org/10.17712/nsj.2018.2.20170132

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  • Table 1

    Interrelationship between diabetes mellitus and depression.

    Diabetes and depression exist as independent conditions
    Diabetes with its complications acts as a risk factor for development of depression
    Depression acts as risk factor for the development of diabetes
    Development of diabetes secondary to antidepressant therapy
  • Table 2

    Interrelationship between Schizophrenia and diabetes mellitus.

    Schizophrenia is often associated with metabolic abnormalities.
    Schizophrenia is an independent risk factor for diabetes mellitus
    Early detection of diabetes in schizophrenic patient is very important
    More cognitive impairment if schizophrenia and diabetes are co-associated
    Non-adherence to treatment in schizophrenic patients results in poor glycemic control
  • Table 3

    Commonly prescribed antipsychotic drugs.

    First generation antipsychotic drugs (Typical psychotropic medications)Second generation antipsychotic drugs (Atypical psychotic medications)
    Amitriptyline-perphenazineAmisulpride
    ChlorpromazineAripiprazole
    FluphenazineClozapine
    HaloperidolIloperidone
    LoxapineLurasidone
    PromazineOlanzapine
    Sulpiridepaliperidone,
    TrifluoperazineQuetiapine
    Ziprasidone
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