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Research ArticleOriginal Article
Open Access

Frequency, risk factors, and outcomes in patients with significant carotid artery disease admitted to King Abdulaziz Medical City, Riyadh with Ischemic Stroke

Misealreem A. Shaheen, Areej A. Albelali, Raghad M. AlKanhal, Muneera K. AlSaqabi, Raghad M. AlTurki, Raghad S. AlAskar, Altaf H. Khan and Ismail A. Khatri
Neurosciences Journal October 2019, 24 (4) 264-268; DOI: https://doi.org/10.17712/nsj.2018.4.20190046
Misealreem A. Shaheen
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Areej A. Albelali
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Raghad M. AlKanhal
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Muneera K. AlSaqabi
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Raghad M. AlTurki
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Raghad S. AlAskar
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Altaf H. Khan
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Ismail A. Khatri
From King Abdulaziz Medical City, MNGHA (Khatri), King Saud bin Abdulaziz University for Health Sciences (Shaheen, Albelali, AlKanhal, AlSaqabi, AlTurki, AlAskar, Khatri), King Abdullah International Medical Research Center (Khan, Khatri), Riyadh, Kingdom of Saudi Arabia.
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Article Figures & Data

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    Figure 1

    Likelihood ratios of risk factors in patients with significant and nonsignificant carotid artery disease (CAD).

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    Figure 2

    Pattern of intervention in the significant group, treated group (dark black bars), and nontreated group (dotted bars).

Tables

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    Table 1

    Frequency of various risk factors in the whole group and significant carotid artery disease (CAD) and nonsignificant CAD subgroups.

    Carotid artery Group
    Risk factorsNonsignificant groupSignificant groupP-value
    n=395n=40
    n (%)
    Gender
    Male248 (62.78)25 (62.5)0.972
    Female147 (37.22)15 (37.5)
    Diabetes
    Yes245 (62.03)31 (77.5)0.053
    No150 (37.97)9 (22.5)
    Obesity
    Yes162 (41.01)9 (22.5)0.022
    No233(58.99)31 (77.5)
    Smoking
    Yes72 (18.22)10 (25.0)0.298
    No323 (81.78)30 (75.0)
    Prior stroke
    Yes65 (16.46)8 (20)0.298
    No330 (83.54)32 (80)
    Dyslipidemia
    Yes149 (37.72)18 (45)0.367
    No246 (62.28)22 (55)
    Migraine
    Yes5 (1.27)1 (2.5)0.4414
    No390 (98.73)39 (97.5)
    Hypertension
    Yes282 (71.39)33 (82.5)0.134
    No113 (28.61)7 (17.5)
    Ischemic heart disease
    Yes56 (14.18)8 (20)0.322
    No339 (85.82)32 (80)
    Transient ischemic attack
    Yes10 (2.53)2 (5)0.304
    No385 (97.47)38 (95)
    • View popup
    Table 2

    A comparison of risk factors in patients with significant and nonsignificant carotid artery disease (CAD).

    ParameterAnalysis of Penalized Maximum Likelihood Estimates
    DFEstimateStandard ErrorWald chi-squarePr > chi-squareOdds ratio(95% confidence intervals)
    GenderFemale vs. Male10.53630.39411.85180.17361.71 (0.76-3.77)
    DiabetesYes vs. No10.58280.41321.98980.15841.79 (0.81-4.28)
    ObesityYes vs. No1-1.03100.39316.87820.00870.36 (0.15-0.76)
    SmokingYes vs. No10.69320.42502.66120.10282.00 (0.84-4.58)
    Prior strokeYes vs. No10.31980.43740.53460.46471.38 ((0.55-3.16)
    DyslipidemiaYes vs. No10.33690.34180.97130.32441.40 (0.71-2.76)
    MigraineYes vs. No10.97521.05770.85010.35652.65 (0.25-15.33)
    HypertensionYes vs. No10.42180.45930.84340.35841.53 (0.63-4.05)
    Ischemic heart diseaseYes vs. No.10.28430.43390.42950.51221.33 (0.54-3.01)
    Transient ischemic attackYes vs. No10.63000.79400.62970.42751.88 (0.33-7.43)
    Atrial fibrillationYes vs. No10.89090.64201.92590.16522.44 (0.60-7.67)
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Neurosciences Journal: 24 (4)
Neurosciences Journal
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1 Oct 2019
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Frequency, risk factors, and outcomes in patients with significant carotid artery disease admitted to King Abdulaziz Medical City, Riyadh with Ischemic Stroke
Misealreem A. Shaheen, Areej A. Albelali, Raghad M. AlKanhal, Muneera K. AlSaqabi, Raghad M. AlTurki, Raghad S. AlAskar, Altaf H. Khan, Ismail A. Khatri
Neurosciences Journal Oct 2019, 24 (4) 264-268; DOI: 10.17712/nsj.2018.4.20190046

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Frequency, risk factors, and outcomes in patients with significant carotid artery disease admitted to King Abdulaziz Medical City, Riyadh with Ischemic Stroke
Misealreem A. Shaheen, Areej A. Albelali, Raghad M. AlKanhal, Muneera K. AlSaqabi, Raghad M. AlTurki, Raghad S. AlAskar, Altaf H. Khan, Ismail A. Khatri
Neurosciences Journal Oct 2019, 24 (4) 264-268; DOI: 10.17712/nsj.2018.4.20190046
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