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Systematic ReviewSystematic Review
Open Access

Management of Lennox-Gastaut syndrome with deep brain stimulation: A systematic literature review

Rahaf F. Alanazi and Ahmed M. Alkhani
Neurosciences Journal October 2022, 27 (4) 216-220; DOI: https://doi.org/10.17712/nsj.2022.4.20220043
Rahaf F. Alanazi
From the College of Medicine (Alanazi), King Saud Bin Abdulaziz University for Health Sciences, and from the Division of Neurosurgery (Alkhani), Department of Surgery, King Abdulaziz Medical City, Ministry of the National Guard–Health Affairs, Riyadh, Kingdom of Saudi Arabia.
MBBS
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  • For correspondence: [email protected]
Ahmed M. Alkhani
From the College of Medicine (Alanazi), King Saud Bin Abdulaziz University for Health Sciences, and from the Division of Neurosurgery (Alkhani), Department of Surgery, King Abdulaziz Medical City, Ministry of the National Guard–Health Affairs, Riyadh, Kingdom of Saudi Arabia.
MD, FRCS(C), IFAANS
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    - Flow diagram of the literature search process for selecting studies for the systematic review.

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    Table 1

    - Systematic literature review.

    AuthorYearNo. of LGS patientsSurgical approachOutcome of interestReported adverse eventSeizure reduction
    Aaron E.L. Warren202220Targeting CMNOptimal target and connectivity for DBS in LGSN=1 cerebral infection>52%
    Byung-chul Son20164Targeting CMNClinical outcomes and location of active contactsN=1 Misplacement of bilateral DBS leads30% -100%
    F. Velasco200726Targeting CMNClinical outcomes and location of active contactsNone53% - 100%

    LGS -Lennox-Gastaut syndrome, CMN - centromedian thalamic nucleus, DBS - deep brain stimulation

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    1 Oct 2022
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    Management of Lennox-Gastaut syndrome with deep brain stimulation: A systematic literature review
    Rahaf F. Alanazi, Ahmed M. Alkhani
    Neurosciences Journal Oct 2022, 27 (4) 216-220; DOI: 10.17712/nsj.2022.4.20220043

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    Management of Lennox-Gastaut syndrome with deep brain stimulation: A systematic literature review
    Rahaf F. Alanazi, Ahmed M. Alkhani
    Neurosciences Journal Oct 2022, 27 (4) 216-220; DOI: 10.17712/nsj.2022.4.20220043
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    © 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

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