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Research ArticleOriginal Article
Open Access

Elevated level of creatine phosphokinase in newborn: Clinical significance and association with congenital muscle diseases

Waleed A. Al-twaijri, Saif A. Al-saif, Ghina I. Al-fehaid, Muhannad Q. Al-qirnas and Emad M. Masuadi
Neurosciences Journal October 2022, 27 (4) 263-269; DOI: https://doi.org/10.17712/nsj.2022.4.20220051
Waleed A. Al-twaijri
From the Department of Pediatrics (Al-twaijri), King Abdullah Specialist Children Hospital, Department of pediatrics, King Abdulaziz Medical City (Al-saif), Central region, and from the College of Medicine (Al-fehaid, Al-qirnas, Masuadi), king Saud Bin Abdulaziz University For Health Sciences Riyadh, Kingdom of Saudi Arabia
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  • For correspondence: [email protected]
Saif A. Al-saif
From the Department of Pediatrics (Al-twaijri), King Abdullah Specialist Children Hospital, Department of pediatrics, King Abdulaziz Medical City (Al-saif), Central region, and from the College of Medicine (Al-fehaid, Al-qirnas, Masuadi), king Saud Bin Abdulaziz University For Health Sciences Riyadh, Kingdom of Saudi Arabia
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Ghina I. Al-fehaid
From the Department of Pediatrics (Al-twaijri), King Abdullah Specialist Children Hospital, Department of pediatrics, King Abdulaziz Medical City (Al-saif), Central region, and from the College of Medicine (Al-fehaid, Al-qirnas, Masuadi), king Saud Bin Abdulaziz University For Health Sciences Riyadh, Kingdom of Saudi Arabia
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Muhannad Q. Al-qirnas
From the Department of Pediatrics (Al-twaijri), King Abdullah Specialist Children Hospital, Department of pediatrics, King Abdulaziz Medical City (Al-saif), Central region, and from the College of Medicine (Al-fehaid, Al-qirnas, Masuadi), king Saud Bin Abdulaziz University For Health Sciences Riyadh, Kingdom of Saudi Arabia
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Emad M. Masuadi
From the Department of Pediatrics (Al-twaijri), King Abdullah Specialist Children Hospital, Department of pediatrics, King Abdulaziz Medical City (Al-saif), Central region, and from the College of Medicine (Al-fehaid, Al-qirnas, Masuadi), king Saud Bin Abdulaziz University For Health Sciences Riyadh, Kingdom of Saudi Arabia
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  • Figure 1
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    Figure 1

    - Correlation between the age of the neonate and the first CPK value

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    Figure 2

    - Distribution of the first CPK value.

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    Figure 3

    - Distribution of the log value of the first CPK measurement.

Tables

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    Table 1

    - Maternal and neonatal demographics.

    Demographicsn(%)
    Maternal age  
    <40465(92.3)
    40+39(7.7)
    Maternal body mass index groups  
    Underweight0(0)
    Normal54(10.7)
    Overweight144(28.6)
    Obese306(60.7)
    Maternal blood types  
    O252(50)
    B104(20.6)
    A125(24.8)
    AB23(4.6)
    Gravidity  
    1106(21.7)
    2105(21.5)
    379(16.2)
    461(12.5)
    558(11.9)
    6+79(16.2)
    Parity  
    0107(22.1)
    1109(22.5)
    2101(20.8)
    358(12)
    458(12)
    5+52(10.7)
    Types of delivery  
    Normal spontaneous vaginal delivery335(66.5)
    Elective cesarean section102(20.2)
    Emergency cesarean section67(13.3)
    Neonatal sex  
    Male253(50.2)
    Female251(49.8)
    Blood type of neonates  
    O253(50.2)
    B100(19.8)
    A132(26.2)
    AB19(3.8)
    Apgar score at 1 minute of age  
    41(0.2)
    52(0.4)
    69(1.9)
    78(1.7)
    840(8.3)
    9421(87.5)
    Apgar score at 5 minute of age  
    85(1)
    9473(98.3)
    103(0.6)
    • View popup
    Table 2

    - Neonatal anthropometric parameters.

    ParametersnMinimumMaximumMeanStd. Deviation
    Abdominal circumference497204730.72.2
    Chest circumference49024.53832.61.7
    Head circumference49530.55334.41.5
    Birth weight5042.014.643.080.42
    Birth height504365650.12.3
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Neurosciences Journal: 27 (4)
Neurosciences Journal
Vol. 27, Issue 4
1 Oct 2022
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Elevated level of creatine phosphokinase in newborn: Clinical significance and association with congenital muscle diseases
Waleed A. Al-twaijri, Saif A. Al-saif, Ghina I. Al-fehaid, Muhannad Q. Al-qirnas, Emad M. Masuadi
Neurosciences Journal Oct 2022, 27 (4) 263-269; DOI: 10.17712/nsj.2022.4.20220051

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Elevated level of creatine phosphokinase in newborn: Clinical significance and association with congenital muscle diseases
Waleed A. Al-twaijri, Saif A. Al-saif, Ghina I. Al-fehaid, Muhannad Q. Al-qirnas, Emad M. Masuadi
Neurosciences Journal Oct 2022, 27 (4) 263-269; DOI: 10.17712/nsj.2022.4.20220051
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