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Research ArticleOriginal Article
Open Access

Changes in routine blood parameters of patients with generalized tonic clonic seizure: a retrospective study

Jiankang Huang, Jun Yang, Jiali Miao and Hongbo Wen
Neurosciences Journal April 2023, 28 (2) 123-129; DOI: https://doi.org/10.17712/nsj.2023.2.20220135
Jiankang Huang
From the Department of Neurology, Nanjing Lishui People’s Hospital, Zhongda Hospital Lishui Branch, Southeast University, Jiangshu Province, China.
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  • For correspondence: [email protected]
Jun Yang
From the Department of Neurology, Nanjing Lishui People’s Hospital, Zhongda Hospital Lishui Branch, Southeast University, Jiangshu Province, China.
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Jiali Miao
From the Department of Neurology, Nanjing Lishui People’s Hospital, Zhongda Hospital Lishui Branch, Southeast University, Jiangshu Province, China.
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Hongbo Wen
From the Department of Neurology, Nanjing Lishui People’s Hospital, Zhongda Hospital Lishui Branch, Southeast University, Jiangshu Province, China.
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    Figure 1

    - Change in the RBC and PLT count in GTCS patient. RBC - red blood cell, PLT - platelet, GTCS - generalized tonic clonic seizure

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    Figure 2

    - Changes in the WBC count in GTCS patients

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    Table 1

    - Demographical and clinical features of subjects.

    ParametersGTCS GroupControl GroupP-value
    (n=45)(n=200)
    Male (%)25 (55.6)105 (55.6)0.711
    Age (year)63.7±15.265.3±9.20.505
    Hypertension (%)14 (31)68 (34)0.844
    Diabetes (%)13 (28.9)56 (28)0.905
    Cr (µmol/L)6.29±1.517.99±4.850.358
    Ur (mmol/L)68.9±13.561.2±18.70.387
    ALT (U/L)22.4±7.231.2±18.10.220
    AST (U/L)23.1±5.724.8±6.80.592
    ALT - alanine aminotransferase, AST - aspartate aminotransferase, Ur - urea, Cr - creatinine, GTCS - Generalized tonic clonic seizure
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    Table 2

    - Routine blood parameters in GTCS patients with different seizure duration.

    ParametersGTCS durationP-value
    ≤5 min (n=20)>5 min (n=25)
    Red blood cell count (1012/L)4.61±0.894.66±1.070.891
    Platelet count (109/L)184±66179±650.779
    White blood cell count (109/L)8.23±2.6511.96±4.200.001
    Neutrophil count (109/L)5.70±1.618.65±4.090.002
    Lymphocyte count (109/L)2.15±1.392.74±1.940.254
    NLR4.09±3.516.02±6.740.224
    NLR - neutrophil to lymphocyte ratio, GCTS - generalized tonic clonic seizure
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Neurosciences Journal: 28 (2)
Neurosciences Journal
Vol. 28, Issue 2
1 Apr 2023
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Changes in routine blood parameters of patients with generalized tonic clonic seizure: a retrospective study
Jiankang Huang, Jun Yang, Jiali Miao, Hongbo Wen
Neurosciences Journal Apr 2023, 28 (2) 123-129; DOI: 10.17712/nsj.2023.2.20220135

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Changes in routine blood parameters of patients with generalized tonic clonic seizure: a retrospective study
Jiankang Huang, Jun Yang, Jiali Miao, Hongbo Wen
Neurosciences Journal Apr 2023, 28 (2) 123-129; DOI: 10.17712/nsj.2023.2.20220135
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