Article Figures & Data
Figures
- Figure 1
- This graph shows the miRNAs expressional fold changes between healthy controls and CA cases, the mean expression of the controls was set as 1 in which we considered it to be the reference point to measure the expressional fold changes of the cases in regard to this reference point.
- Figure 2
- MiRNA expression of CA cases based on gender, showing almost the doubling of miRNA-143 in males in comparison to females.
- Figure 3
- miRNA expression based on the multiplicity of aneurysms, showing higher expression among cases who had a single aneurysm in comparison to those who had two aneurysms.
- Figure 4
- miRNA expression based on the presence aneurysmal rupture, miRNA-143 was highly expressed among cases who had aneurysmal rupture.
Tables
Case Age Gender Aneurysm details Comorbid/Causative Conditions miRNA Expression fold change No. of Aneurysm Site Ruptured Heart disease Stroke Diabetes HTN Smoker miRNA-16 miRNA-143 miRNA-200a-3p 1 51 M 1 AcomA Yes, SAH No No No Yes No 6.92 1.97 4.02 2 50 F 1 AcomA Yes, SAH Yes No Yes Yes No 9.65 12.9 4.67 3 23 M 1 AcomA Yes, SAH No No No No No 8.5 5.81 4.47 4 38 M 1 AcomA Yes, SAH No No No No No 11.48 2.89 8.77 5 31 F 1 Lt, internal carotid No No Yes No No No 3.86 2.23 3.66 6 42 F 1 Lt, Paraophtalmic Yes, SAH No No No No No 1.56 3.42 1.51 7 52 F 2 Rt, paraophtalmic artery No No No Yes Yes No 22.58 11.4 4.26 8 30 M 2 Lt, MCA Yes, SAH No No No No Yes 7.44 18.49 11.03 9 34 F 1 Rt, ICA No No Yes No Yes No 6.16 6.98 13.63 10 39 F 1 Rt, Picom + AcomA Yes, SAH No No No Yes No 7.19 10.02 13.43 11 49 M 1 Lt, ICA Yes, SAH No No No Yes Yes 62.8 76.04 26.79 12 58 F 1 Lt, MCA Yes, SAH No No No No Yes 0.83 0.32 0.83 13 63 F 1 Ant choroidal No No No Yes Yes No 74.75 29.74 42.79 14 45 M 1 Lt, posterior comA artery Yes, SAH No No No No Yes 15.75 22.81 17.5 15 52 F 1 AcomA No Yes Yes No Yes No 0.54 1.42 1.3 16 46 F 1 Rt, MCA No No No No No No 1.75 8.53 5.05 17 65 M 2 Rt, MCA + Lt, ICA No No No Yes Yes Yes 0.3 0.16 0.38 Mean fold change 14.24 12.65 9.65 CA -Cerebral aneurysm, SAH - subarachnoid hemorrhage, MCA - middle cerebral artery, ICA - internal carotid
Status of Condition miRNA-143 miRNA-200 miRNA-16 Stroke No 14.61 10.39 16.54 Yes 3.54 6.20 3.52 HTN No 8.06 6.60 6.40 Yes 16.74 12.36 21.21 Diabetes No 12.38 8.61 10.37 Yes 13.55 13.03 26.82 Heart Disease No 13.53 9.80 15.40 Yes 6.13 8.55 5.53 Smoker No 9.17 9.49 12.76 Yes 21.02 10.04 17.79 Vasospasm No 14.41 10.68 16.73 Yes 8.45 7.18 8.26
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