Article Figures & Data
Figures
- Figure 1
- Incidence of acute stroke patients developing Contrast-Induced Nephropathy (CIN) following CT angiography brain.
Tables
- Table 1
- Bio-demographic characteristics of acute stroke patients developing contrast-induced nephropathy following CT angiography brain.
Data Total CIN P-value Yes No No (%) No (%) No (%) Incidence of CIN 182 15 (8.24) 167 (91.8) Age in years < 40 14 (7.7) 1 (7.1) 13 (92.9) .322 40-59 80 (44.0) 4 (5.0) 76 (95.0) 60+ 88 (48.4) 10 (11.4) 78 (88.6) Gender Male 120 (65.9) 9 (7.5) 111 (92.5) .613 Female 62 (34.1) 6 (9.7) 56 (90.3) Risk factors Diabetes Mellitus 93 (51.1) 7 (7.5) 86 (92.5) .049**$ Hypertension 109 (59.9) 10 (9.2) 99 (90.8) Smoking 21 (11.5) 0 (0.0) 21 (100.0) Ischemic heart disease 34 (18.7) 3 (8.8) 31 (91.2) Epilepsy 4 (2.2) 0 (0.0) 4 (100.0) Atrial fibrillation 5 (2.7) 0 (0.0) 5 (100.0) Heart failure 4 (2.2) 0 (0.0) 4 (100.0) CKD 4 (2.2) 2 (50.0) 2 (50.0) Unknown 38 (20.9) 3 (7.9) 35 (92.1) Large vessel occlusion Yes 44 (24.3) 4 (9.1) 40 (90.9) .824$ No 137 (75.7) 11 (8.0) 126 (92.0) Thrombectomy Yes 33 (18.1) 2 (6.1) 31 (93.9) .615$ No 149 (81.9) 13 (8.7) 136 (91.3) TPA Yes 39 (21.4) 7 (17.9) 32 (82.1) .013*$ No 143 (78.6) 8 (5.6) 135 (94.4) - Table 2
- Multiple logistic regression analysis for predictors of developing contrast-induced nephropathy among acute stroke patients underwent brain CT angiography.
Factors B S.E. P-value ORA 95% CI Lower Upper Age in years 0.04 0.03 .123 1.04 0.99 1.10 Male gender 0.21 0.71 .769 1.23 0.31 5.10 Diabetes Mellitus -0.67 0.72 .353 0.51 0.13 2.10 Hypertension 0.69 0.03 .045* 2.10 1.29 6.98 Smoking -0.55 1.27 .664 0.57 0.05 6.99 Ischemic heart disease -0.25 0.89 .778 0.78 0.13 4.48 Large vessel occlusion 0.35 0.93 .711 1.41 0.23 8.79 Thrombectomy -0.73 1.04 .481 0.48 0.06 3.69 TPA 1.97 0.72 .007* 7.15 1.73 29.59 ICH 1.92 0.87 .027* 6.66 1.23 33.31 fever -0.38 1.24 .760 0.69 0.06 7.76 Abnormal baseline 2.06 0.77 .007* 7.82 1.74 35.11 Seizures 0.12 1.06 .910 1.13 0.14 9.07 B - regression coefficient, SE - Standard error, ORA - Adjusted odds ration, CI - Confidence interval,
↵* p< 0.05 (significant),
ICH - intracerebral hemorrhage, TPA - tissue plasminogen
- Table 3
- Clinical data characteristics of acute stroke patients developing contrast-induced nephropathy following CT angiography brain.
Clinical data Total CIN P-value Yes No No (%) No (%) No (%) Diagnosis ICH 19 (10.4) 4 (21.1) 15 (78.9) .150 Ischemic stroke 134 (73.6) 10 (7.5) 124 (92.5) Mimics 9 (4.9) 0 (0.0) 9 (100.0) TIA 20 (11.0) 1 (5.0) 19 (95.0) Fever 1st 48 hours Yes 5 (2.9) 0 (0.0) 5 (100.0) .487 No 170 (97.1) 15 (8.8) 155 (91.2) Abnormal serum creatinine baseline Yes 21 (11.6) 5 (23.8) 16 (76.2) .006* No 160 (88.4) 10 (6.3) 150 (93.8) Seizures Yes 15 (8.2) 2 (13.3) 13 (86.7) .454 No 167 (91.8) 13 (7.8) 154 (92.2) Length of hospital stay 1-6 days 71 (39.0) 4 (26.7) 67 (40.1) .655 7-14 days 54 (29.7) 6 (40.0) 48 (28.7) 15-30 days 27 (14.8) 3 (20.0) 24 (14.4) >30 days 30 (16.5) 2 (13.3) 28 (16.8) At hospital death Yes 29 (15.9) 8 (53.3) 21 (12.6) .001* No 146 (80.2) 7 (46.7) 139 (83.2) Unknown 7 (3.8) 0 (0.0) 7 (4.2) Other factors Mean±SD p-value # NIHSS score in ER 10.3±7.0 17.0±6.4 9.7±6.7 .001* ECHO – Ejection fraction 55.3±10.7 51.6±15.0 55.5±10.3 .322 Hemoglobin 13.9±9.6 11.8±2.4 14.1±9.9 .360 Highest WBCs count 1st 48 hours 9.9±4.6 11.1±4.9 9.8±4.5 .279 HbA1c 7.1±2.1 6.7±2.1 7.2±2.1 .620 Highest glucose level 220.1±152.3 305.3±155.7 214.7±151.1 .049* LDL 102.5±49.7 111.4±54.1 101.9±49.7 .652
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