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Research ArticleOriginal Article
Open Access

Comparing the clinical efficacy of preganglionic and preganglionic plus ganglionic transforaminal epidural steroid injections for lumbosacral radicular pain

Hamit Göksu, Şeref Celik, Erkan Y. Akcaboy, Şaziye Şahin, Müge Baran, Gökhan Yıldız, Samet S. Kaya and Mustafa Y. Ayhan
Neurosciences Journal January 2025, 30 (1) 44-48; DOI: https://doi.org/10.17712/nsj.2025.1.20240064
Hamit Göksu
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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  • ORCID record for Hamit Göksu
  • For correspondence: [email protected]
Şeref Celik
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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Erkan Y. Akcaboy
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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Şaziye Şahin
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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Müge Baran
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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Gökhan Yıldız
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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Samet S. Kaya
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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Mustafa Y. Ayhan
From the Department of Algology (Göksu), Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, from the Department of Algology (Celik, Akcaboy, Şahin), University of Health Sciences Ankara City Hospital, Ankara, from Ankara Gaziler PMR Training and Research Hospital (Baran), University of Health Sciences, Ağrı, from the Department of Algology (Yıldız), University of Health Sciences Ankara Etlik City Hospital, Ankara, from the Department of Algology (Kaya), Adıyaman University Training and Research Hospital, Adıyaman, and from the Department of Algology (Ayhan), Dumlupinar University Kutahya Evliya Celebi Training and Research Hospital, Kütahya, Turkey.
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    Table 1

    - Demographic and clinical features of the patients according to group.

     Preganglionic group (n=31)Preganglionic and postganglionic group (n=35)P-value
    Mean±standard deviation
    Age(years)45.42±13.5145.66±12.20.940a
    Gender (n/%)
    Female16(51.6)22(62.9).356b
    Male15(4.4)13(37.1)
    Side of pain (n/%)
    Right18(58.1)13(37.1).089b
    Left13(41.9)22(62.9)
    Disc level (n/%)
    L3–45(16.1)2(5.7).248b
    L4–515(39.5)23(65.7)
    L5–S111(35.5)10(28.6)
    Duration of pain (weeks)15.78±13.5816.91±12.89.728a
    NRS – pretreatment7.90±1.168.06±0.99.565a
    NRS – third week4.45±2.743.29±2.17.059a
    PSS – third week2.26±1.362.69±1.40.216a
    NRS – third month4.55±2.604.23±2.54.616a
    PSS – thirdmonth2.03±1.492.31±1.53.453a

    NRS =numeric rating scale; PSS=patient satisfaction scale

    • ↵a Independent samples t-test;

    • ↵b chi-squared test;

    • View popup
    Table 2

    - Comparison of groups in terms of PSS scores over time

     Preganglionic group (n=31)Preganglionic plus ganglionic group (n=35)P-value*
    PSSN/% 
    At third week
    Poor3 (9.7)3 (8.6)0.352
    Fair8 (25.8)5 (14.3)
    Good6 (19.4)8 (22.9)
    Very good6 (19.4)3 (8.6)
    Excellent8 (11.3)16 (45.7)
    At third month
    Poor7 (6.1)6 (17.1)0.671
    Fair5 (5.6)7 (20.0)
    Good6 (19.4)3 (8.6)
    Very good6 (19.4)8 (22.9)
    Excellent7 (22.6)11 (31.4)
    • ↵* Chi-squared test; PSS =patient satisfaction scale

    • View popup
    Table 3

    - Correlation analysis for variables associated with meaningful pain relief.

    VariablesMeaningful pain relief at third weekMeaningful pain relief at third month
    Age
    Rho-.131-.278
    P.296.024*
    Gender
    Rho.281.256
    P.022*.038*
    Pain duration prior to treatment
    Rho-.120-.203
    P.337.102
    Disc lesion level
    Rho0.47.045
    P.708.721
    Preganglionic or preganglionic plus ganglionic group
    Rho.180.071
    P.147.573
    • ↵* A p-value less than 0.05 is considered to be statistically significant

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Comparing the clinical efficacy of preganglionic and preganglionic plus ganglionic transforaminal epidural steroid injections for lumbosacral radicular pain
Hamit Göksu, Şeref Celik, Erkan Y. Akcaboy, Şaziye Şahin, Müge Baran, Gökhan Yıldız, Samet S. Kaya, Mustafa Y. Ayhan
Neurosciences Journal Jan 2025, 30 (1) 44-48; DOI: 10.17712/nsj.2025.1.20240064

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Comparing the clinical efficacy of preganglionic and preganglionic plus ganglionic transforaminal epidural steroid injections for lumbosacral radicular pain
Hamit Göksu, Şeref Celik, Erkan Y. Akcaboy, Şaziye Şahin, Müge Baran, Gökhan Yıldız, Samet S. Kaya, Mustafa Y. Ayhan
Neurosciences Journal Jan 2025, 30 (1) 44-48; DOI: 10.17712/nsj.2025.1.20240064
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