Research ArticleOriginal Article
Open Access

Electrophysiologic severity of carpal tunnel syndrome in diabetic patients of the Saudi population

Saima Nazish, Azra Zafar, Rizwana Shahid, Abdullah Al Sulaiman, Majed Alabdali, Danah Aljaafari, Fahad A. Alkhamis, Zakia M. Yasawy, Noman Ishaque, Nehad M. Soltan and Ejaz A. Vohra
Neurosciences Journal January 2019, 24 (1) 22-28; DOI: https://doi.org/10.17712/nsj.2019.1.20180217

Article Figures & Data

Tables

  • Table 1

    Demographic and clinical characteristics of cases with CTS (N=200).

    Characteristicsn (%)
    Gender
     Male34 (17)
     Female166 (83)
    Mean Age and range (Years)54.4±11.9 (27-96)
    CTS sites
     Bilateral131 (65.5)
     Unilateral69 (34.5)
     Right46 (23)
     left23 (11.5)
    Non recordable nerves29 (14.5)
    CTS risk factors
     Diabetic112 (56)
     Non-Diabetic88 (44)
    Other risk factors
     Hypertension90 (45)
     Dyslipidemia127 (63.5)
     Obesity146 (73)
     Hypothyroidism15 (7.5)
     Rheumatoid arthritis2 (1)
     Corticosteroid use1 (0.5)
    Body parameters Mean±SD
     Height156.5±7.7
     Weight83±16.1
     BMI34.1±6.5
     Systolic BP135±16.1
     Diastolic BP78±8.6
    Lab parameters Mean±SD
     Serum cholesterol (<=200mg/dl)180.8±39.9
     Serum LDL (<100mg/dl)110±34.4
     Serum HDL (35-60mg/dl)51.4±15.1
     Serum triglyceride (<=150mg/dl)115.4±69.1
     Fasting blood sugar (70-99mg/dl)128±54.8
     Mean HBa1c and range (4.5-13.4)6.9±1.76 (4-6)

    • CTS - carpal tunnel syndrome, HBa1c - glycosylated hemoglobin type A1C, BMI - body mass index, BP - blood pressure, LDL - low-density lipoprotein, HDL - high density lipoprotein, SD - standard deviation.

  • Table 2

    Description of demography and prevalence of other CTS risk factors among diabetic and non-diabetic with CTS in study population (N=200).

    VariablesDiabetic (n=140)Non-diabetic (n=104)P-value*
    n (%)
    Gender
     Male23 (20.5)11 (12.5)0.13
     Female89 (79.5)77 (87.5)
    Hypertension61 (54.5)29 (33.3)0.003
    Dyslipidemia74 (66.1)53 (60.2)0.39
    Obesity90 (80.4)56 (63.3)0.01
    Hypothyroidism7 (6.3)8 (9.1)0.44
    Rheumatoid arthritis0 (0)2 (2.3)0.10
    Steroid therapy1 (0.9)0 (0)0.37

    • ↵* Chi-square test, CTS - carpal tunnel syndrome

  • Table 3

    Description of electrophysiologic parameters and comparison among diabetic and non-diabetic.

    Electrophysiologic parameterDiabeticNon-diabeticP-value
    Mean±SD
    MNSOL4.4±0.84.2±1.20.19*
    MNSA19.6±11.523.7±12.80.02*
    MNSCV40.8±7.843.2±12.60.08*
    MNDML4.7±1.14.6±1.30.42*
    MNMA7.8±2.68.7±6.50.19*
    MNMCV54.2±26.454.8±7.40.84*
    Non recordable nerves, n (%)23 (20.5)6 (6.8)0.005†
    Bilateral CTS, n (%)83 (74)48 (54.5)0.004†

    • ↵* Independent sample t-test,

    • ↵† Chi-square test, MNSOL - median nerve sensory onset latency, MNSA - median nerve sensory amplitude, MNSCV - median nerve sensory conduction velocity, MNDML - median nerve motor distal latency, MNMA - median nerve motor amplitude, MNMCV - median nerve motor conduction velocity, CTS - carpal tunnel syndrome, SD - standard deviation

  • Table 4

    Comparison of CTS severity in patients with and without diabetes.

    Electrophysiologic parameter severityCTS handsDiabeticNon-diabeticP-value*
    n (%)
    Very Mild CTS34 (17)12 (10.7)23 (25)0.006
    Mild CTS155 (77.5)86 (77.7)65 (77.3)0.88
    Moderate CTS45 (22.5)28 (27.7)14 (16)0.14
    Severe CTS48 (24)29 (25.9)19 (21.6)0.50
    Very severe CTS26 (9.4)11 (9.9)5 (9.1)0.36
    Extremely severe CTS31 (15.5)27 (24.1)4 (4.5)<0.005

    • ↵* Chi-square test, CTS - carpal tunnel syndrome.

  • Table 5

    Comparison of factors that could affect the severity electrophysiological findings among diabetic and non-diabetic patients.

    Risk factorsDiabeticNon-diabeticP-value*
    Mean±SD
    Age57.6±11.0550.3±11.7<0.001
    BMI35.3±6.932.5±5.60.002
    Systolic BP137.8±6.9131.4±6.90.005
    Diastolic BP79±6.977.6±6.90.24
    Serum cholesterol175±41.0188±37.50.02
    Serum LDL105±33.3116±34.90.02
    Serum HDL48.1±14.855.6±14.3<0.001
    Serum triglyceride134.7±78.991±43.7<0.001
    Fasting sugar152.1±62.697.3±13.2<0.001
    HBa1c7.6±1.85.6±0.35<0.001

    • ↵* Independent sample t-test.

    • BMI - body mass index, BP - blood pressure, LDL - low-density lipoprotein, HDL - high density lipoprotein, HBa1c - glycosylated hemoglobin type A1C, SD - standard deviation.

Back to top

In this issue

Print
Download PDF
Email Article
Citation Tools
Bookmark this article

Jump to section