Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • Saudi Medical Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Neurosciences Journal
  • Other Publications
    • Saudi Medical Journal
  • My alerts
  • Log in
Neurosciences Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors

Murad Alturkustani
Neurosciences Journal July 2024, 29 (3) 168-176; DOI: https://doi.org/10.17712/nsj.2024.3.20230108
Murad Alturkustani
From the Department of Pathology, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, and from the Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada
MBBS, FRCPC
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Murad Alturkustani
  • For correspondence: [email protected]
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Jaunmuktane Z,
    2. Capper D,
    3. Jones DTW,
    4. Schrimpf D,
    5. Sill M,
    6. Dut M, et al.
    Methylation Array Profiling of Adult Brain Tumours: Diagnostic Outcomes in a Large, Single Centre. Acta Neuropathol Commun 2019; 7: 24.
    OpenUrl
  2. 2.
    1. Priesterbach-Ackley LP,
    2. Boldt HB,
    3. Petersen JK,
    4. Bervoets N,
    5. Scheie, D,
    6. Ulhøi BP, et al.
    Brain Tumour Diagnostics Using a DNA Methylation-Based Classifier as a Diagnostic Support Tool. Neuropathol Appl Neurobiol 2020; 46: 478-492.
    OpenUrlCrossRefPubMed
  3. 3.↵
    1. Capper D,
    2. Stichel D,
    3. Sahm F,
    4. Jones DTW,
    5. Schrimpf D,
    6. Sill, M, et al.
    Practical Implementation of DNA Methylation and Copy-Number-Based CNS Tumor Diagnostics: The Heidelberg Experience. Acta Neuropathol 2018; 136: 181-210.
    OpenUrl
  4. 4.↵
    1. Sturm D,
    2. Capper D,
    3. Andreiuolo F,
    4. Gessi M,
    5. Kölsche C,
    6. Reinhardt A, et al.
    Multiomic Neuropathology Improves Diagnostic Accuracy in Pediatric Neuro-Oncology. Nat Med 2023; 29: 917-926.
    OpenUrlCrossRef
  5. 5.↵
    1. Schindler G,
    2. Capper D,
    3. Meyer J,
    4. Janzarik W,
    5. Omran H,
    6. Herold-Mende C, et al.
    Analysis of BRAF V600E Mutation in 1,320 Nervous System Tumors Reveals High Mutation Frequencies in Pleomorphic Xanthoastrocytoma, Ganglioglioma and Extra-Cerebellar Pilocytic Astrocytoma. Acta Neuropathol 2011; 121: 397-405.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.↵
    1. Horbinski C,
    2. Nikiforova MN,
    3. Hagenkord JM,
    4. Hamilton RL,
    5. Pollack IF
    . Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas. Neuro Oncol 2012; 14: 777-789,
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Perry A,
    2. Capper D,
    3. Ellison DW,
    4. Jones DTW,
    5. Reifenberger G
    . Diffuse Leptomeningeal Glioneuronal Tumour. In: WHO Classification of Tumours Editorial Board, editors. Central nervous system tumours; WHO classification of Tumours series. Lyon (France): International Agency for Research on Cancer; 2021.
  8. 8.↵
    1. Alturkustani M
    . Diffuse GFAP Immunopositivity in the Oligodendrocyte-like Component of Pilocytic Astrocytoma Distinguishes It from Mimickers. Diagnostics (Basel) 2022; 12: 1632.
    OpenUrl
  9. 9.↵
    1. Alturkustani M
    . Classification of Pediatric Gangliogliomas Based on the Histological Infiltration. Curr Oncol 2022; 29: 6764-6775.
    OpenUrl
  10. 10.↵
    1. Reinhardt A,
    2. Pfister K,
    3. Schrimpf D,
    4. Stichel D,
    5. Sahm F,
    6. Reuss DE, et al.
    Anaplastic Ganglioglioma-A Diagnosis Comprising Several Distinct Tumour Types. Neuropathol Appl Neurobiol 2022; 48: e12847.
    OpenUrl
  11. 11.↵
    1. Gupta K,
    2. Orisme W,
    3. Harreld JH,
    4. Qaddoumi I,
    5. Dalton JD,
    6. Punchihewa C, et al.
    Posterior Fossa and Spinal Gangliogliomas Form Two Distinct Clinicopathologic and Molecular Subgroups. Acta Neuropathol Commun 2014; 2: 18.
    OpenUrl
  12. 12.↵
    1. Collins VP,
    2. Jones DTW,
    3. Giannini C
    . Pilocytic Astrocytoma: Pathology, Molecular Mechanisms and Markers. Neuropathol Appl Neurobiol 2022; 48: e12847.
    OpenUrl
  13. 13.↵
    1. Capper D,
    2. Jones DTW,
    3. Sill M,
    4. Hovestadt V,
    5. Schrimpf D,
    6. Sturm D, et al.
    DNA Methylation-Based Classification of Central Nervous System Tumours. Nature 2018; 555: 469-474.
    OpenUrlCrossRefPubMed
  14. 14.↵
    1. Alturkustani M
    . Diagnostic Insights into Pediatric Pleomorphic Xanthoastrocytoma through DNA Methylation Class and Pathological Diagnosis Analysis. Diagnostics (Basel) 2023; 13: 3464.
    OpenUrl
  15. 15.↵
    1. Vaubel R,
    2. Zschernack V,
    3. Tran QT,
    4. Jenkins S,
    5. Caron A,
    6. Milosevic D, et al.
    Biology and Grading of Pleomorphic Xanthoastrocytoma-What Have We Learned about It? Brain Pathol 2021; 31: 20-32.
    OpenUrl
  16. 16.↵
    1. Giannini C,
    2. Capper D,
    3. Figarella-Branger D,
    4. Jacques TS,
    5. Jones DTW,
    6. Louis DN, et al.
    In WHO Classification of Tumours Editorial Board. Central nervous system tumours.; WHO classification of Tumours series.; International Agency for Research on Cancer: Lyon (France), 2021; 6: 94–99.
    OpenUrl
PreviousNext
Back to top

In this issue

Neurosciences Journal: 29 (3)
Neurosciences Journal
Vol. 29, Issue 3
1 Jul 2024
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Neurosciences Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors
(Your Name) has sent you a message from Neurosciences Journal
(Your Name) thought you would like to see the Neurosciences Journal web site.
Citation Tools
Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors
Murad Alturkustani
Neurosciences Journal Jul 2024, 29 (3) 168-176; DOI: 10.17712/nsj.2024.3.20230108

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors
Murad Alturkustani
Neurosciences Journal Jul 2024, 29 (3) 168-176; DOI: 10.17712/nsj.2024.3.20230108
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Acknowledgement
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Ranking the difficulty of the cognitive tasks in Dual-Tasks during walking in healthy adults
  • Exploring physiotherapist’s ability to identify cauda equina syndrome early
  • Does the severity of facet joint osteoarthritis affect facet medial branch radiofrequency thermocoagulation results?
Show more Original Article

Similar Articles

Navigate

  • home

More Information

  • Help

Additional journals

  • All Topics

Other Services

  • About

© 2025 Neurosciences Journal Neurosciences is copyright under the Berne Convention and the International Copyright Convention. All rights reserved. Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3183. Print ISSN 1319-6138.

Powered by HighWire