Research ArticleOriginal Article
Open Access

The clinicopathological features and prognosis of multifocal high-grade gliomas in adults with H3F3A mutation

Yongrui Zhao, Yidong Chen, Leiming Wang, Ying Gao and Jiankun Xu
Neurosciences Journal January 2023, 28 (1) 42-47; DOI: https://doi.org/10.17712/nsj.2023.1.20220080

References

  1. 1.↵
    1. Wu G,
    2. Broniscer A,
    3. McEachron TA,
    4. Lu C,
    5. Paugh BS,
    6. Becksfort J, et al.
    Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 2012; 44: 251-253.
    OpenUrlCrossRefPubMed
  2. 2.↵
    1. Roux A,
    2. Pallud J,
    3. Saffroy R,
    4. Edjlali-Goujon M,
    5. Debily MA,
    6. Boddaert N, et al.
    High-grade gliomas in adolescents and young adults highlight histomolecular differences from their adult and pediatric counterparts. Neuro Oncol 2020; 22: 1190-1202.
    OpenUrlCrossRefPubMed
  3. 3.↵
    1. Meyronet D,
    2. Esteban-Mader M,
    3. Bonnet C,
    4. Joly MO,
    5. Uro-Coste E,
    6. Amiel-Benouaich A, et al.
    Characteristics of H3 K27M-mutant gliomas in adults. Neuro Oncol 2017; 19: 1127-1134.
    OpenUrlCrossRefPubMed
  4. 4.↵
    1. Picart T,
    2. Barritault M,
    3. Poncet D,
    4. Berner LP,
    5. Izquierdo C,
    6. Tabouret E, et al.
    Characteristics of diffuse hemispheric gliomas, H3 G34-mutant in adults. Neurooncol Adv 2021; 3: 1-12.
    OpenUrl
  5. 5.↵
    1. Sturm D,
    2. Witt H,
    3. Hovestadt V,
    4. Khuong-Quang DA,
    5. Jones DT,
    6. Konermann C, et al.
    Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012; 22: 425-437.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.↵
    1. Louis DN,
    2. Perry A,
    3. Wesseling P,
    4. Brat DJ,
    5. Cree IA,
    6. Figarella-Branger D, et al.
    The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol 2021; 23: 1231-1251.
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Haque W,
    2. Thong Y,
    3. Verma V,
    4. Rostomily R,
    5. Brian Butler E,
    6. Teh BS.
    Patterns of management and outcomes of unifocal versus multifocal glioblastoma. J Clin Neurosci 2020; 74: 155-159.
    OpenUrl
  8. 8.↵
    1. Di Carlo DT,
    2. Cagnazzo F,
    3. Benedetto N,
    4. Morganti R,
    5. Perrini P.
    Multiple high-grade gliomas: epidemiology, management, and outcome. A systematic review and meta-analysis. Neurosurg Rev 2019; 42: 263-275.
    OpenUrl
  9. 9.↵
    1. Louis DN,
    2. Perry A,
    3. Reifenberger G,
    4. von Deimling A,
    5. Figarella-Branger D,
    6. Cavenee WK, et al.
    The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. (Berl.) 2016; 131: 803-820.
    OpenUrlCrossRefPubMed
  10. 10.↵
    1. Paulsson AK,
    2. Holmes JA,
    3. Peiffer AM,
    4. Miller LD,
    5. Liu W,
    6. Xu J, et al.
    Comparison of clinical outcomes and genomic characteristics of single focus and multifocal glioblastoma. J Neurooncol 2014; 119: 429-435.
    OpenUrlCrossRefPubMed
  11. 11.↵
    1. Thomas RP,
    2. Xu LW,
    3. Lober RM,
    4. Li G,
    5. Nagpal S.
    The incidence and significance of multiple lesions in glioblastoma. J Neurooncol 2013; 112: 91-97.
    OpenUrlCrossRefPubMed
  12. 12.↵
    1. Vuong HG,
    2. Ngo TNM,
    3. Le HT, et al.
    The prognostic significance of HIST1H3B/C and H3F3A K27M mutations in diffuse midline gliomas is influenced by patient age. J Neurooncol 2022; 158: 405-412.
    OpenUrl
  13. 13.↵
    1. López-Pérez CA,
    2. Franco-Mojica X,
    3. Villanueva-Gaona R,
    4. Díaz-Alba A,
    5. Rodríguez-Florido MA,
    6. Navarro VG.
    Adult diffuse midline gliomas H3 K27-altered: review of a redefined entity. J Neurooncol 2022; 158: 369-378.
    OpenUrl
  14. 14.↵
    1. Wang L,
    2. Shao L,
    3. Li H,
    4. Yao K,
    5. Duan Z,
    6. Zhi C, et al.
    Histone H3.3 G34-mutant Diffuse Gliomas in Adults. Am J Surg Pathol 2022; 46: 249-257.
    OpenUrl
  15. 15.↵
    1. Korshunov A,
    2. Capper D,
    3. Reuss D,
    4. Schrimpf D,
    5. Ryzhova M,
    6. Hovestadt V, et al.
    Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity. Acta Neuropathol 2016; 131: 137-146.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Wang L,
    2. Li Z,
    3. Zhang M,
    4. Piao Y,
    5. Chen L,
    6. Liang H, et al.
    H3 K27M-mutant diffuse midline gliomas in different anatomical locations. Hum Pathol 2018; 78: 89-96.
    OpenUrl
  17. 17.↵
    1. Louis DN,
    2. Wesseling P,
    3. Aldape K,
    4. Brat DJ,
    5. Capper D,
    6. Cree IA, et al.
    cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading. Brain Pathol 2020; 30: 844-856.
    OpenUrlCrossRefPubMed
  18. 18.↵
    1. Lim JX,
    2. Leong A,
    3. Tan AP,
    4. Tan CL,
    5. Nga VDW.
    H3K27M-mutant diffuse midline glioma presenting as synchronous lesions involving pineal and suprasellar region: A case report and literature review. J Clin Neurosci 2020; 81: 144-148.
    OpenUrl
  19. 19.↵
    1. Wang Q,
    2. Niu W,
    3. Pan H.
    Targeted therapy with anlotinib for a H3K27M mutation diffuse midline glioma patient with PDGFR-α mutation: a case report. Acta Neurochir (Wien) 2022; 164: 2063-2066.
    OpenUrl
  20. 20.↵
    1. Yekula A,
    2. Gupta M,
    3. Coley N,
    4. Sang U H.
    Adult H3K27M-mutant diffuse midline glioma with gliomatosis cerebri growth pattern: Case report and review of the literature. Int J Surg Case Rep 2020; 68: 124-128.
    OpenUrlCrossRefPubMed
  21. 21.↵
    1. Schulte JD,
    2. Buerki RA,
    3. Lapointe S,
    4. Molinaro AM,
    5. Zhang Y,
    6. Villanueva-Meyer JE, et al.
    Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adults. Neurooncol Adv 2020; 2: 1-10.
    OpenUrl
  22. 22.↵
    1. Vettermann FJ,
    2. Felsberg J,
    3. Reifenberger G,
    4. Hasselblatt M,
    5. Forbrig R,
    6. Berding G, et al.
    Characterization of Diffuse Gliomas With Histone H3-G34 Mutation by MRI and Dynamic 18F-FET PET. Clin Nucl Med 2018; 43: 895-898.
    OpenUrl
  23. 23.↵
    1. Kay MD,
    2. Pariury HE,
    3. Perry A,
    4. Winegar BA,
    5. Kuo PH.
    Extracranial Metastases From Glioblastoma With Primitive Neuronal Components on FDG PET/CT. Clin Nucl Med 2020; 45: e162-e164.
    OpenUrl
  24. 24.
    1. Jethanandani A,
    2. Gule-Monroe MK,
    3. Chen M,
    4. Johnson JM.
    Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation. Front Oncol 2019; 9: 373.
    OpenUrl
  25. 25.↵
    1. Mohiuddin S,
    2. Maraka S,
    3. Usman Baig M,
    4. Gupta S,
    5. Muzzafar T,
    6. Valyi-Nagy T, et al.
    Case series of diffuse extraneural metastasis in H3F3A mutant high-grade gliomas: Clinical, molecular phenotype and literature review. J Clin Neurosci 2021; 89: 405-411.
    OpenUrl
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